P
Pedro Cesar Chagastelles
Researcher at Universidade Federal do Rio Grande do Sul
Publications - 30
Citations - 3250
Pedro Cesar Chagastelles is an academic researcher from Universidade Federal do Rio Grande do Sul. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 16, co-authored 30 publications receiving 3035 citations. Previous affiliations of Pedro Cesar Chagastelles include Pontifícia Universidade Católica do Rio Grande do Sul.
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Journal ArticleDOI
Mesenchymal stem cells reside in virtually all post-natal organs and tissues
TL;DR: The results suggest that the distribution of MSCs throughout the post-natal organism is related to their existence in a perivascular niche, which has implications for understanding MSC biology, and for clinical and pharmacological purposes.
Journal ArticleDOI
Methodology, biology and clinical applications of mesenchymal stem cells.
Melissa Camassola,Luisa Maria Gomes de Macedo Braga,Pedro Cesar Chagastelles,Nance Beyer Nardi +3 more
TL;DR: C cultured MSCs were found to secrete various bioactive molecules that display anti-apoptotic, immunomodulatory, angiogenic, anti-scarring, and chemoattracted properties, providing a basis for their use as tools to create local regenerative environments in vivo.
Journal ArticleDOI
Co-transplantation of mesenchymal stem cells maintains islet organisation and morphology in mice
Chloe L. Rackham,Pedro Cesar Chagastelles,Nance Beyer Nardi,Astrid C Hauge-Evans,Peter M. Jones,Aileen King +5 more
TL;DR: Co-transplantation of islets with MSCs had a profound impact on the remodelling process, maintaining islet organisation and improving islet revascularisation and also improved the capacity of islet grafts to reverse hyperglycaemia.
Journal ArticleDOI
Biology of stem cells: an overview.
TL;DR: This review aims at presenting, to health professionals interested in this area, an overview on the biology of embryonic and adult stem cells, and their therapeutic potential.
Journal ArticleDOI
Pre-culturing islets with mesenchymal stromal cells using a direct contact configuration is beneficial for transplantation outcome in diabetic mice
Chloe L. Rackham,Paramjeet Dhadda,Pedro Cesar Chagastelles,Sian Simpson,Anshi Anjili Dattani,James E. Bowe,Peter M. Jones,Aileen King +7 more
TL;DR: Pre-culturing islets with MSCs using a direct contact configuration maintains functional β-cell mass in vitro and the capacity of cultured islets to reverse hyperglycemia in diabetic mice is investigated.