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Pedro Cesar Chagastelles

Researcher at Universidade Federal do Rio Grande do Sul

Publications -  30
Citations -  3250

Pedro Cesar Chagastelles is an academic researcher from Universidade Federal do Rio Grande do Sul. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 16, co-authored 30 publications receiving 3035 citations. Previous affiliations of Pedro Cesar Chagastelles include Pontifícia Universidade Católica do Rio Grande do Sul.

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Mesenchymal stem cells reside in virtually all post-natal organs and tissues

TL;DR: The results suggest that the distribution of MSCs throughout the post-natal organism is related to their existence in a perivascular niche, which has implications for understanding MSC biology, and for clinical and pharmacological purposes.
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Methodology, biology and clinical applications of mesenchymal stem cells.

TL;DR: C cultured MSCs were found to secrete various bioactive molecules that display anti-apoptotic, immunomodulatory, angiogenic, anti-scarring, and chemoattracted properties, providing a basis for their use as tools to create local regenerative environments in vivo.
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Co-transplantation of mesenchymal stem cells maintains islet organisation and morphology in mice

TL;DR: Co-transplantation of islets with MSCs had a profound impact on the remodelling process, maintaining islet organisation and improving islet revascularisation and also improved the capacity of islet grafts to reverse hyperglycaemia.
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Biology of stem cells: an overview.

TL;DR: This review aims at presenting, to health professionals interested in this area, an overview on the biology of embryonic and adult stem cells, and their therapeutic potential.
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Pre-culturing islets with mesenchymal stromal cells using a direct contact configuration is beneficial for transplantation outcome in diabetic mice

TL;DR: Pre-culturing islets with MSCs using a direct contact configuration maintains functional β-cell mass in vitro and the capacity of cultured islets to reverse hyperglycemia in diabetic mice is investigated.