Lutz Langbein

TL;DR: Since keratins also exhibit characteristic expression patterns in human tumors, several of them have great importance in immunohistochemical tumor diagnosis of carcinomas, in particular of unclear metastases and in precise classification and subtyping.

TL;DR: This revised nomenclature accommodates functional genes and pseudogenes, and although designed specifically for the full complement of human keratins, it offers the flexibility needed to incorporate additional keratin proteins from other mammalian species.

TL;DR: The genomic organization of the human hair keratin gene family and the complex expression characteristics of hair keratins in the hair-forming compartment are described and the role and fate ofhair keratin in the diseased hair follicle is described.

TL;DR: The human type I hair keratin subfamily comprises nine individual members, which can be subdivided into three groups as mentioned in this paper : group A (hHa1, hHa3-I, hHA3-II, hHHa4), group B (hHHa7, HHa8), and group C (hHA5, hEH6, HEH8).

TL;DR: expression of EpCAM, claudin-7, CO-029, and CD44v6 expression was up-regulated in colon cancer and liver metastasis and coexpression and complex formation of the molecules was correlated with clinical variables and apoptosis resistance.