M
María-Julieta González
Researcher at University of Chile
Publications - 69
Citations - 4101
María-Julieta González is an academic researcher from University of Chile. The author has contributed to research in topics: Salivary gland & Unfolded protein response. The author has an hindex of 24, co-authored 64 publications receiving 2476 citations. Previous affiliations of María-Julieta González include Queen's University.
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Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases.
Daniela Parada Venegas,Marjorie De la Fuente,Glauben Landskron,María-Julieta González,Rodrigo Quera,Gerard Dijkstra,Hermie J. M. Harmsen,Klaas Nico Faber,Marcela A. Hermoso +8 more
TL;DR: An overview of microbial SCFAs production and their effects on the intestinal mucosa with specific emphasis on their relevance for Inflammatory Bowel Diseases is presented and the therapeutic potential ofSCFAs for IBD is discussed.
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Characterization of the Novel ST2/IL-33 System in Patients with Inflammatory Bowel Disease
Caroll J. Beltrán,Lucía Núñez,David Díaz-Jiménez,Nancy Farfán,Enzo Candia,Claudio Heine,Francisco López,María-Julieta González,Rodrigo Quera,Marcela A. Hermoso +9 more
TL;DR: The novel association between the ST2/IL‐33 system and IBD seems to identify that variations in this axis might regulate the inflammatory process in these diseases.
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Corrigendum: Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases (Frontiers in Immunology (2019) 10 (277) DOI: 10.3389/fimmu.2019.00277)
Daniela Parada Venegas,Marjorie De la Fuente,Glauben Landskron,María-Julieta González,Rodrigo Quera,Gerard Dijkstra,Hermie J. M. Harmsen,Klaas Nico Faber,Marcela A. Hermoso +8 more
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Disruption of tight junction structure in salivary glands from Sjögren's syndrome patients is linked to proinflammatory cytokine exposure
Patricia Ewert,Sergio Aguilera,Cecilia Alliende,Yoon-Jeoung Kwon,Amelina Albornoz,Claudio Molina,Ulises Urzúa,Andrew F. G. Quest,Nancy Olea,Paola Pérez,Isabel Castro,María-José Barrera,Rafael Romo,Marcela A. Hermoso,Cecilia Leyton,María-Julieta González +15 more
TL;DR: The findings indicate that local cytokine production in LSGs from SS patients may contribute to the secretory gland dysfunction observed in SS patients by altering tight junction integrity of epithelial cells, thereby decreasing the quality and quantity of saliva.
Journal ArticleDOI
Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes.
Paola Marambio,Barbra Toro,Carlos Sanhueza,Rodrigo Troncoso,Valentina Parra,Hugo Verdejo,Lorena García,Clara Quiroga,Daniela B. Munafó,Jessica Díaz-Elizondo,Roberto Bravo,María-Julieta González,Guilermo Diaz-Araya,Zully Pedrozo,Mario Chiong,María Isabel Colombo,Sergio Lavandero +16 more
TL;DR: Glucose deprivation induces oxidative stress which is associated with aggresome formation and activation of autophagy in cultured cardiac myocytes and ROS inhibition by N-acetylcysteine or by the adenoviral overexpression of catalase or superoxide dismutase disrupted aggresomes formation and Autophagy induced by glucose deprivation.