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Lorena García

Researcher at University of Chile

Publications -  86
Citations -  6676

Lorena García is an academic researcher from University of Chile. The author has contributed to research in topics: ATPase & Heart failure. The author has an hindex of 26, co-authored 86 publications receiving 5294 citations. Previous affiliations of Lorena García include Pontifical Catholic University of Chile & Valparaiso University.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Counter-regulatory renin-angiotensin system in cardiovascular disease

María Paz Ocaranza, +7 more
- 01 Feb 2020 - 
TL;DR: The latest insights are provided into the complexity and interplay of the components of the non-canonical renin–angiotensin system, and the function and therapeutic potential of targeting this system to treat cardiovascular disease.
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Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes.

Paola Marambio, +16 more
- 01 Jun 2010 - 
TL;DR: Glucose deprivation induces oxidative stress which is associated with aggresome formation and activation of autophagy in cultured cardiac myocytes and ROS inhibition by N-acetylcysteine or by the adenoviral overexpression of catalase or superoxide dismutase disrupted aggresomes formation and Autophagy induced by glucose deprivation.
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New Molecular Insights of Insulin in Diabetic Cardiomyopathy.

Francisco Westermeier, +9 more
- 12 Apr 2016 - 
TL;DR: The role of insulin in this pathology is reviewed and the discussion of new molecular insights which may help to understand its underlying mechanisms and generate possible new therapeutic strategies are discussed.
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Fibroblast Primary Cilia Are Required for Cardiac Fibrosis.

Elisa Villalobos, +21 more
- 14 May 2019 - 
TL;DR: Findings point to a pivotal role of this organelle, and PC1, in disease-related pathological cardiac remodeling and suggest that some of the cardiovascular manifestations of autosomal dominant polycystic kidney disease derive directly from myocardium-autonomous abnormalities.