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Mark E. Mummert

Researcher at University of North Texas Health Science Center

Publications -  36
Citations -  1719

Mark E. Mummert is an academic researcher from University of North Texas Health Science Center. The author has contributed to research in topics: Antigen presentation & T cell. The author has an hindex of 20, co-authored 36 publications receiving 1609 citations. Previous affiliations of Mark E. Mummert include University of Texas Southwestern Medical Center & University of North Texas.

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Generation and function of reactive oxygen species in dendritic cells during antigen presentation.

TL;DR: These results provide both conceptual and technical frameworks for studying ROS-dependent regulation of DC-T cell communication during Ag presentation and for testing the potential utility of antioxidants for the treatment of immunological disease.
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Development of a Peptide Inhibitor of Hyaluronan-Mediated Leukocyte Trafficking

TL;DR: It is document that HA plays an essential role in “two-way” trafficking of leukocytes to and from an inflamed tissue, and thus provide technical and conceptual bases for testing the potential efficacy of HA inhibitors (e.g., Pep-1) for inflammatory disorders.
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Contrasting Impacts of Immunosuppressive Agents (Rapamycin, FK506, Cyclosporin A, and Dexamethasone) on Bidirectional Dendritic Cell-T Cell Interaction During Antigen Presentation

TL;DR: These results demonstrate contrasting pharmacological effects of RAP vs calcineurin inhibitors on Ag presentation, thus forming a conceptual framework for rationale-based selection (and combination) of immunosuppressive agents for clinical application.
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Psychological Stress and the Cutaneous Immune Response: Roles of the HPA Axis and the Sympathetic Nervous System in Atopic Dermatitis and Psoriasis.

TL;DR: Understanding how the activity of the psyche-nervous -immune system axis impinges on skin diseases may facilitate coordinated treatment strategies between dermatologists and psychiatrists is highlighted.
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Immunologic roles of hyaluronan

TL;DR: Far from an inert structural biopolymer, HA represents a multifunctional carbohydrate mediator of immune processes.