Mary Ahrens

TL;DR: These cancer genetic counseling recommendations describe the medical, psychosocial, and ethical ramifications of identifying at-risk individuals through cancer risk assessment with or without genetic testing.

TL;DR: There is interest in developing clinical programs for familial cancers by NCI-supported cancer centers, but most of these programs are in developmental stages; a base line has been established to monitor future progress for the provision of cancer genetic services.

TL;DR: Findings indicate that vismodegib may also block alternate, non-canonical forms of downstream SHH pathway activation, which provides strong impetus for further investigation of vismODEgib in clinical trials in the first-line setting for pediatric and adult forms of medulloblastoma.

TL;DR: A higher than expected proportion of female heterozygous for the R141Q mutation were clinically and biochemically symptomatic but remained undiagnosed for many years and should be performed in females who present with a combination of relatively non-specific symptoms.

TL;DR: Analysis of written responses yielded four themes: Made Decision, Sought Information, Expressed Thoughts/Feelings, and No Decision, which rated the non-disclosing counselor significantly lower in social attractiveness than either disclosing counselor, and less satisfying than the professional disclosing counselor.