Mika Ito

TL;DR: In this article, the authors reviewed the immunological environment in normal pregnancy and complicated pregnancy from the viewpoint of the new Th1/Th2/Th17 and Treg paradigms.

TL;DR: In the early pregnancy decidua, lymphocytes express some activation markers on their surface, suggesting that maternal lymphocytes are activated and recognize the semiallograftic fetus, and the immunoregulation system must work to prevent fetus rejection.

TL;DR: Nakashima et al. as mentioned in this paper investigated the level of peripheral Th17 cells in healthy pregnancy subjects and found that most of the Th17-producing cells were CD4+ T cells.

TL;DR: Citation Nakashima A, Ito M, Shima T, Bac ND, Hidaka T, Saito S. Accumulation of IL‐17‐positive cells in decidua of inevitable abortion cases is found to be a cause for concern.

TL;DR: IL-17A may play a role in the development of endometriosis by stimulating inflammatory responses and proliferation of ESCs and enhanced the expression of cyclooxygensase-2 mRNA and proliferationof ESCs.