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Neil A. R. Gow
Researcher at University of Exeter
Publications - Â 391
Citations - Â 37511
Neil A. R. Gow is an academic researcher from University of Exeter. The author has contributed to research in topics: Candida albicans & Corpus albicans. The author has an hindex of 95, co-authored 377 publications receiving 33060 citations. Previous affiliations of Neil A. R. Gow include Marischal College & University Hospital of Lausanne.
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Journal ArticleDOI
Hidden Killers: Human Fungal Infections
Gordon D. Brown,David W. Denning,Neil A. R. Gow,Stuart M. Levitz,Mihai G. Netea,Theodore C. White +5 more
TL;DR: The importance of fungi as human pathogens is highlighted and the challenges the authors face in combating the devastating invasive infections caused by these microorganisms are discussed, in particular in immunocompromised individuals.
Journal ArticleDOI
Antifungal agents: mechanisms of action
TL;DR: The sordarins represent a novel class of agents that inhibit fungal protein synthesis, and three are echinocandins, which inhibit synthesis of fungal cell wall polysaccharides--a new mode of action.
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Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
Geraldine Butler,Matthew D. Rasmussen,Michael F. Lin,Michael F. Lin,Manuel A. S. Santos,Sharadha Sakthikumar,Carol A. Munro,Esther Rheinbay,Esther Rheinbay,Manfred Grabherr,Anja Forche,Jennifer L. Reedy,Ino Agrafioti,Martha B. Arnaud,Steven Bates,Alistair J. P. Brown,Sascha Brunke,Maria C. Costanzo,David A. Fitzpatrick,Piet W. J. de Groot,David Harris,Lois L. Hoyer,Bernhard Hube,Frans M. Klis,Chinnappa D. Kodira,Nicola Lennard,Mary E. Logue,Ronny Martin,Aaron M. Neiman,Elissavet Nikolaou,Michael A. Quail,Janet Quinn,Maria C. Santos,Florian F. Schmitzberger,Gavin Sherlock,Prachi Shah,Kevin A. T. Silverstein,Marek S. Skrzypek,David R. Soll,Rodney Staggs,Ian Stansfield,Michael P. H. Stumpf,Peter E. Sudbery,Thyagarajan Srikantha,Qiandong Zeng,Judith Berman,Matthew Berriman,Joseph Heitman,Neil A. R. Gow,Michael C. Lorenz,Bruce W. Birren,Manolis Kellis,Manolis Kellis,Christina A. Cuomo +53 more
TL;DR: There are significant expansions of cell wall, secreted and transporter gene families in pathogenic species, suggesting adaptations associated with virulence in Candida albicans species.
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An integrated model of the recognition of Candida albicans by the innate immune system.
TL;DR: The fungal pathogen Candida albicans is used as a model for the complex interaction that exists between the host pattern-recognition systems and invading microbial pathogens.
Journal ArticleDOI
The distinct morphogenic states of Candida albicans.
TL;DR: It is argued that studies on "filamentous forms" should always include a formal analysis to determine whether the cells are hyphae or pseudohyphae and some simple experimental criteria that can be applied to achieve this are suggested.