N
Niels Olsen Saraiva Câmara
Researcher at University of São Paulo
Publications - 304
Citations - 9145
Niels Olsen Saraiva Câmara is an academic researcher from University of São Paulo. The author has contributed to research in topics: Immune system & Inflammation. The author has an hindex of 47, co-authored 263 publications receiving 6876 citations. Previous affiliations of Niels Olsen Saraiva Câmara include State University of Campinas & Imperial College London.
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Journal ArticleDOI
Intestinal barrier and gut microbiota: Shaping our immune responses throughout life.
TL;DR: This review will be focused on the development of the intestinal barrier and its function in host immune defense and how gut microbiome composition throughout life can affect this role.
Journal ArticleDOI
The Macrophage Switch in Obesity Development.
Angela Castoldi,Cristiane Naffah de Souza,Niels Olsen Saraiva Câmara,Niels Olsen Saraiva Câmara,Pedro M. Moraes-Vieira +4 more
TL;DR: The immunologic and metabolic functions of AT macrophages and their different facets in obesity and the metabolic syndrome are reviewed.
Journal ArticleDOI
Gut Bacteria Products Prevent AKI Induced by Ischemia-Reperfusion
Vinicius Andrade-Oliveira,Mariane Tami Amano,Matheus Correa-Costa,Angela Castoldi,Raphael José Ferreira Felizardo,Danilo Candido de Almeida,Ênio José Bassi,Pedro M. Moraes-Vieira,Meire Ioshie Hiyane,Andrea C.D. Rodas,Jean Pierre Schatzmann Peron,Cristhiane Favero Aguiar,Marlene Antônia dos Reis,Willian R. Ribeiro,Claudete J. Valduga,Rui Curi,Marco Aurélio Ramirez Vinolo,Caroline M. Ferreira,Niels Olsen Saraiva Câmara,Niels Olsen Saraiva Câmara +19 more
TL;DR: It is demonstrated that SCFAs improve organ function and viability after an injury through modulation of the inflammatory process, most likely via epigenetic modification.
Journal ArticleDOI
Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism.
José Luís Fachi,Jaqueline de Souza Felipe,Laís Passariello Pral,Bruna Karadi da Silva,Renan O. Corrêa,Mirella Cristiny Pereira de Andrade,Denise Morais da Fonseca,Paulo José Basso,Niels Olsen Saraiva Câmara,Éricka Lorenna de Sales e Souza,Flaviano S. Martins,Suzana Eiko Sato Guima,Andrew Maltez Thomas,João C. Setubal,João C. Setubal,Yuli Thamires Magalhães,Fabio Luis Forti,Thamiris Candreva,Hosana G. Rodrigues,Marcelo Bispo de Jesus,Sílvio Roberto Consonni,Alessandro S. Farias,Patrick Varga-Weisz,Patrick Varga-Weisz,Marco Aurélio Ramirez Vinolo +24 more
TL;DR: It is concluded that butyrate protects intestinal epithelial cells from damage caused by C. difficile-induced colitis via the stabilization of HIF-1, mitigating local inflammatory response and systemic consequences of the infection.
Journal ArticleDOI
Inflammation in Renal Diseases: New and Old Players.
Vinicius Andrade-Oliveira,Vinicius Andrade-Oliveira,Orestes Foresto-Neto,Ingrid Kazue Mizuno Watanabe,Ingrid Kazue Mizuno Watanabe,Roberto Zatz,Niels Olsen Saraiva Câmara,Niels Olsen Saraiva Câmara +7 more
TL;DR: The most recent evidence that renal inflammation can be ameliorated by interfering with the gut microbiota through the administration of probiotics, prebiotics, and postbiotics is summarized and the recent discovery of new targets for drugs long in use in clinical practice is addressed.