P
Phillip Lerche
Researcher at Ohio State University
Publications - 46
Citations - 816
Phillip Lerche is an academic researcher from Ohio State University. The author has contributed to research in topics: Isoflurane & Anesthetic. The author has an hindex of 14, co-authored 43 publications receiving 697 citations.
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The cardiorespiratory and anesthetic effects of clinical and supraclinical doses of alfaxalone in cats.
TL;DR: Alfaxalone produced dose-dependent anesthesia, cardiorespiratory depression and unresponsiveness to noxious stimulation in unpremedicated cats.
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Noninvasive estimation of central venous pressure in anesthetized dogs by measurement of hepatic venous blood flow velocity and abdominal venous diameter
TL;DR: In this paper, the authors measured hepatic vein, caudal vena cava (CVC) diameter, and hepatic venous flow velocities using pulsed wave Doppler ultrasound.
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Comparison of four drug combinations for total intravenous anesthesia of horses undergoing surgical removal of an abdominal testis.
William W. Muir,Phillip Lerche,J. T. Robertson,John A. E. Hubbell,Warren L. Beard,Tirina Miller,Britton L Badgley,Virgina Bothwell +7 more
TL;DR: Results suggest that all 4 drug combinations can be used to induce short-term anesthesia for abdominal cryptorchidectomy in horses, however, horses receiving TKD had a poorer recovery from anesthesia, often requiring assistance to stand.
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Effect of 50% and maximal inspired oxygen concentrations on respiratory variables in isoflurane-anesthetized horses.
TL;DR: Reducing FiO2 in dorsally recumbent isoflurane anesthetized horses does not improve oxygenation or oxygen delivery and the alveolar to arterial O2 tension difference was increased significantly in both groups during anesthesia compared to preanesthetic values.
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Pharmacokinetics of midazolam after intravenous administration to horses
John A. E. Hubbell,E. M. Kelly,Turi K. Aarnes,Richard M. Bednarski,Phillip Lerche,Zhongfa Liu,Jeffrey Lakritz +6 more
TL;DR: Midazolam produces muscle relaxation but not sedation in adult horses, and drug redistribution is likely the primary mechanism for the termination of effect.