R
Rex C. Haydon
Researcher at University of Chicago
Publications - 172
Citations - 16288
Rex C. Haydon is an academic researcher from University of Chicago. The author has contributed to research in topics: Mesenchymal stem cell & Cellular differentiation. The author has an hindex of 64, co-authored 158 publications receiving 14211 citations. Previous affiliations of Rex C. Haydon include Boston Children's Hospital & Naval Medical Center San Diego.
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Journal ArticleDOI
Osteogenic activity of the fourteen types of human bone morphogenetic proteins (bmps)
Hongwei Cheng,Wei Jiang,Frank M. Phillips,Rex C. Haydon,Ying Peng,Lan Zhou,Hue H. Luu,Naili An,Benjamin N. Breyer,Pantila Vanichakarn,Jan Paul Szatkowski,Jae Yoon Park,Tong-Chuan He +12 more
TL;DR: Bone morphogenic proteins (BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion as mentioned in this paper.
Journal ArticleDOI
A protocol for rapid generation of recombinant adenoviruses using the AdEasy system
Jinyong Luo,Zhong Liang Deng,Zhong Liang Deng,Xiaoji Luo,Xiaoji Luo,Ni Tang,Ni Tang,Wen Xin Song,Jin Chen,Jin Chen,Katie A. Sharff,Hue H. Luu,Rex C. Haydon,Kenneth W. Kinzler,Bert Vogelstein,Tong-Chuan He,Tong-Chuan He +16 more
TL;DR: This protocol describes the practical aspects of using the AdEasy system for generating recombinant adenoviruses and describes the process of generating and testing recombinantAdenoviral plasmids for a variety of purposes.
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Bone Morphogenetic Protein (BMP) signaling in development and human diseases.
Richard N. Wang,Jordan D. Green,Zhongliang Wang,Youlin Deng,Min Qiao,Michael A. Peabody,Qian Zhang,Jixing Ye,Zhengjian Yan,Sahitya K. Denduluri,Olumuyiwa Idowu,Melissa Li,Christine Shen,Alan J. Hu,Rex C. Haydon,Richard W. Kang,James M. Mok,Michael J Lee,Hue L. Luu,Lewis L. Shi +19 more
TL;DR: This review focuses on genetically manipulated mouse knockout models that have helped elucidate the role of BMPs in development and a significant portion of this review is devoted to the prominent human pathologies associated with dysregulated BMP signaling
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Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis.
Yixiao Feng,Yixiao Feng,Mia Spezia,Shifeng Huang,Shifeng Huang,Chengfu Yuan,Chengfu Yuan,Zongyue Zeng,Zongyue Zeng,Linghuan Zhang,Linghuan Zhang,Xiaojuan Ji,Xiaojuan Ji,Wei Liu,Wei Liu,Bo Huang,Bo Huang,Bo Huang,Wenping Luo,Wenping Luo,Bo Liu,Bo Liu,Yan Lei,Yan Lei,Scott Du,Akhila Vuppalapati,Hue H. Luu,Rex C. Haydon,Tong-Chuan He,Guosheng Ren +29 more
TL;DR: Emerging evidence indicates that epigenetic regulations and noncoding RNAs may play important roles in breast cancer development and may contribute to the heterogeneity and metastatic aspects of breast cancer, especially for triple-negative breast cancer.
Journal ArticleDOI
Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery.
Quan Kang,Quan Kang,Sun Mh,Hongwei Cheng,Ying Peng,Anthony G. Montag,Andrea T. Deyrup,Andrea T. Deyrup,Wei Jiang,Hue H. Luu,Jinyong Luo,Jan Paul Szatkowski,Pantila Vanichakarn,Jae Yoon Park,Li Y,Rex C. Haydon,Tong-Chuan He +16 more
TL;DR: Rec recombinant adenoviruses expressing the 14 types of BMPs are used and it is demonstrated that BMP-6 and B MP-9 effectively induced orthotopic ossification when either AdBMP-transduced osteoblast progenitors or the viral vectors were injected into the quadriceps of athymic mice.