Sasha Koul

TL;DR: The protocol demonstrates the ability to reach a core body temperature of <35°C before reperfusion in all patients without delaying primary percutaneous coronary intervention and that combination hypothermia as an adjunct therapy in acute myocardial infarction may reduce infarct size at 3 days as measured by MRI.

TL;DR: The rate of the composite of death from any cause, myocardial infarction, or major bleeding was not lower among those who received bivalirudin than among thosewho received heparin monotherapy, and the results were consistent between patients with STEMI and those with NSTEMI and across other major subgroups.

TL;DR: This study in STEMI patients treated with contemporary mechanical revascularization principles did not show any effect of TRO40303 in limiting reperfusion injury of the ischaemic myocardium.

TL;DR: Overall, deferral of revascularization is equally safe with both iFR and FFR, with a low MACE rate of about 4%.

TL;DR: TT was relatively common following acute coronary syndrome and was associated with a threefold increase in major bleeding compared to DAPT at one year and the HAS-BLED risk score predicted bleeding events with moderate accuracy.