Shlomo Almog

TL;DR: Upon intravenous administration to mice, 2-Ara-Gl caused the typical tetrad of effects produced by THC: antinociception, immobility, reduction of spontaneous activity, and lowering of the rectal temperature.

TL;DR: It is concluded that insulin resistance and/or hyperinsulinemia are present in the majority of hypertensives, constitute a common pathophysiologic feature of obesity, glucose intolerance, and hypertension, possibly explaining their ubiquitous association, and may be linked to the increased peripheral vascular resistance of hypertension, which is putatively related to elevated intracellular sodium concentration.

TL;DR: The identification in porcine brain of arachidonic acid ethanolamide, the structural elucidation, and the synthesis of two novel fatty acid ethanolamides which bind to the cannabinoid receptor are reported.

TL;DR: Interindividual variability in responses to warfarin is attributed to dietary vitamin K, drug interactions, age, or genetic polymorphism in the cytochrome P450 2C9 enzyme (CYP2C9) linked with impaired metabolism of the potent enantiomere S ‐warfarin.

TL;DR: Thiamine repletion can improve left ventricular function and biochemical evidence of thiamine deficiency in some patients with moderate-to-severe CHF who are receiving longterm furosemide therapy.