S
Sylvanie Surget
Researcher at University of Dundee
Publications - 2
Citations - 354
Sylvanie Surget is an academic researcher from University of Dundee. The author has contributed to research in topics: Cancer & Alternative splicing. The author has an hindex of 1, co-authored 1 publications receiving 289 citations.
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Uncovering the role of p53 splice variants in human malignancy: a clinical perspective
TL;DR: The understanding of the regulation of p53 isoform expression and their biological activities in relation to the cellular context would constitute an important step toward the improvement of the diagnostic, prognostic, and predictive values of p 53 in cancer treatment.
Journal ArticleDOI
Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma.
Georgina S F Anderson,José Ballester-Beltrán,George Giotopoulos,Jose A. Guerrero,Sylvanie Surget,James Williams,Tsz So,David Bloxham,Anna Aubareda,Ryan Asby,Ieuan Walker,Lesley Jenkinson,Elizabeth J. Soilleux,James P Roy,Ana Teodósio,Catherine Ficken,Leah Officer-Jones,Sara Nasser,Sheri Skerget,Jonathan J Keats,Peter Greaves,Yu-Tzu Tai,Kenneth C. Anderson,Marion MacFarlane,James Thaventhiran,Brian J. P. Huntly,Paul J. Lehner,Michael A Chapman +27 more
TL;DR: Plasma membrane profiling of primary human myeloma cells is described to identify an unprecedented number of cell surface proteins of a primary cancer, and a novel approach to prioritize immunotherapy targets identified SEMA4A, a cell surface protein not previously implicated inMyeloma, using knock-down by shRNA and CRISPR/dCas9.