Tim J Peters

TL;DR: The comprehensive-cohort design of the ProtecT study provided new insights into trial recruitment and participation decisions, and opportunities to improve recruitment by supporting recruiters with equipoise and patient preferences were identified.

TL;DR: It is demonstrated that identifying high hip fracture risk by FRAX was not associated with any alteration in falls risk, consistent with no impact of screening on falls in women informed to be at high risk of hip fracture.

TL;DR: Evaluating the implications to general practices and the NHS of a change from current policy to one of actively inviting all women with mild dyskaryosis to consult the practice nurse for the intervention finds it both feasible and acceptable for practice nurses to deliver the educational package.

TL;DR: The results show that the relative levels of mt rRNA and mRNA are distinctly regulated in intestinal epithelial cells according to the crypt-villus position and differentiation status of the cells, and that there are higher mt mRNA and mt TFA levels in the crypts, consistent with increased transcriptional activity during mitochondrial biogenesis in the immature enteroblasts.

TL;DR: The data indicate that NF‐E2 is not the primary regulator of intestinal iron absorption, and no relationship was evident between the NF-E2 mRNA levels and the H/L ferritin ratio.