T
Tim J Peters
Researcher at University of Bristol
Publications - 1070
Citations - 51949
Tim J Peters is an academic researcher from University of Bristol. The author has contributed to research in topics: Randomized controlled trial & Population. The author has an hindex of 106, co-authored 1037 publications receiving 47394 citations. Previous affiliations of Tim J Peters include St. Michael's GAA, Sligo & Northwick Park Hospital.
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Rescaling quality of life values from discrete choice experiments for use as QALYs: a cautionary tale
TL;DR: Use of a statistical model such as conditional (multinomial) regression to anchor quality of life values from ordinal data to death is inappropriate in the presence of respondents who do not conform to the assumptions of conventional random utility theory.
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A RANDOMIZED TRIAL COMPARING TRANSURETHRAL RESECTION OF THE PROSTATE, LASER THERAPY AND CONSERVATIVE TREATMENT OF MEN WITH SYMPTOMS ASSOCIATED WITH BENIGN PROSTATIC ENLARGEMENT: THE CLasP STUDY
Jenny L Donovan,Tim J Peters,David E. Neal,Sara T Brookes,Sandeep Gujral,K. Ninan Chacko,Mark Wright,L. Gail Kennedy,Paul Abrams +8 more
TL;DR: Laser therapy and transurethral prostatic resection are effective for decreasing lower urinary tract symptoms and post-void residual urine volume as well as improving quality of life and maximum urinary flow in the short term in men presenting with moderate to severe symptoms.
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Chemical and analytical aspects of areca nut.
TL;DR: A capillary zone electrophoretic method for the rapid analysis of the major alkaloids (arecoline and guavacoline) in areca nut extract is described and is applicable to the analysis of alkaloid in the nut, commercial preparations and in the saliva of areca Nut chewers.
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Systematic review of management of chronic pain after surgery.
Vikki Wylde,Jane A Dennis,Andrew D Beswick,Julie Bruce,Christopher Eccleston,Christopher Eccleston,N. R. Howells,Tim J Peters,Rachael Gooberman-Hill +8 more
TL;DR: The aim of this systematic review was to identify RCTs of interventions for the management of CPSP, and synthesize data across treatment type to estimate their effectiveness and safety.
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Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer
Qian Du,Saul A. Bert,Nicola J. Armstrong,C. E. Caldon,Jenny Z. Song,Shalima S. Nair,Cathryn M. Gould,Phuc-Loi Luu,Tim J Peters,Amanda Khoury,Amanda Khoury,Wenjia Qu,Elena Zotenko,Clare Stirzaker,Clare Stirzaker,Susan J. Clark,Susan J. Clark +16 more
TL;DR: Analysis of prostate and breast cancer genomes and Repli-Seq and integrated epigenome analyses demonstrate that genomic regions that undergo long-range epigenetic deregulation in prostate cancer also show concordant differences in replication timing, and suggests that the nature of chromosomal rearrangement in cancer is related to the spatial and temporal positioning and altered epigenetic states of early-Replicating compared to late-replicating loci.