V
Vasken Ohanian
Researcher at University of Leicester
Publications - 6
Citations - 767
Vasken Ohanian is an academic researcher from University of Leicester. The author has contributed to research in topics: Focal adhesion & Vinculin. The author has an hindex of 5, co-authored 6 publications receiving 745 citations.
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Journal ArticleDOI
The structure and function of α-actinin
TL;DR: A number of distinct isoforms of 0c-actinin have been characterized including the skeletal and smooth muscle isoforms and the non-muscle isoforms isolated from brain, macrophages, platelets, and cultured fibroblasts.
Journal ArticleDOI
Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site
Lance Hemmings,D. J. G. Rees,Vasken Ohanian,S J Bolton,A. P. Gilmore,Bipin Patel,Helen Priddle,J. E. Trevithick,Richard O. Hynes,David R. Critchley +9 more
TL;DR: The results suggest that, although both the N- and C-terminal regions of talin bind actin, the properties of these two regions of the protein are distinct.
Journal ArticleDOI
The cytoskeletal protein talin contains at least two distinct vinculin binding domains.
A. P. Gilmore,C. Wood,Vasken Ohanian,P. Jackson,Bipin Patel,D. J. G. Rees,Richard O. Hynes,David R. Critchley +7 more
TL;DR: By expressing regions of the chicken talin molecule in heterologous cells, it is shown that the sequences required to target talin to focal contacts overlap those which bind vinculin.
Journal ArticleDOI
Cytoskeletal proteins in adherens-type cell-matrix junctions.
David R. Critchley,A. P. Gilmore,Lance Hemmings,Paul Jackson,Alistair P. McGregor,Vasken Ohanian,Bipin Patel,Gillian T. Waites,C. Wood +8 more
TL;DR: 12. Hayley, 1’.
Journal ArticleDOI
Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p
TL;DR: The cytoskeletal protein talin is localised on the cytoplasmic face of the integrin family of adhesion receptors in cellular junctions with the extracellular matrix and is assigned to chromosome 9p, implicated in a variety of cancers.