Werner Hohenberger

TL;DR: This study highlights the greater robustness of CDX2 in comparison to CDX1, and combines digitally‐guided (next generation) TMA construction and digital image analysis to assess accuracy, tumour heterogeneity and the selective impact of different combined intensity‐percentage levels on prognosis.

TL;DR: The study protocol described is feasible without significant acute toxicity and when used the resectability rate was improved; the survival rate, however, was not improved and additional intra-arterial or intraportal application of such drugs as mitomycin C or cisplatin may be necessary.

TL;DR: Fluorescence spectroscopy with a slightly modified conventional light source might be useful for the endoscopic detection of dysplasia and early-stage carcinoma in the upper GI tract.

TL;DR: Treatment of LM from GIST needs a multimodal approach and TKI-therapy is required at any case, but in unresectable cases or recurrent/progressive disease, interventional treatment or TKI escalation should be considered.

TL;DR: Serum concentrations of both mediators were higher in infected patients and the highest concentrations of MCP-1 were in patients who died, illustrating the compartmentalized immune response to intra-abdominal infection.