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Wolfgang M. Kuebler
Researcher at Free University of Berlin
Publications - 46
Citations - 4939
Wolfgang M. Kuebler is an academic researcher from Free University of Berlin. The author has contributed to research in topics: Microcirculation & Lung injury. The author has an hindex of 28, co-authored 46 publications receiving 4136 citations. Previous affiliations of Wolfgang M. Kuebler include Mount Sinai St. Luke's and Mount Sinai Roosevelt & Charité.
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Journal ArticleDOI
An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals
Gustavo Matute-Bello,Gregory P. Downey,Bethany B. Moore,Steve D. Groshong,Michael A. Matthay,Arthur S. Slutsky,Wolfgang M. Kuebler +6 more
TL;DR: This list of features and measurements of ALI is intended as a guide for investigators, and ultimately investigators should choose the particular measurements that best suit the experimental questions being addressed as well as take into consideration any unique aspects of the experimental design.
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Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection.
Christoph B. Messner,Vadim Demichev,Vadim Demichev,Daniel Wendisch,Laura Michalick,Matthew White,Anja Freiwald,Kathrin Textoris-Taube,Spyros I. Vernardis,Anna Sophia Egger,Marco Kreidl,Daniela Ludwig,Christiane Kilian,Federica Agostini,Aleksej Zelezniak,Aleksej Zelezniak,Charlotte Thibeault,Moritz Pfeiffer,Stefan Hippenstiel,Andreas C. Hocke,Christof von Kalle,Archie Campbell,Caroline Hayward,David J. Porteous,Riccardo E. Marioni,Claudia Langenberg,Claudia Langenberg,Kathryn S. Lilley,Wolfgang M. Kuebler,Michael Mülleder,Christian Drosten,Norbert Suttorp,Martin Witzenrath,Florian Kurth,Florian Kurth,Leif E. Sander,Markus Ralser,Markus Ralser +37 more
TL;DR: A platform for ultra-high throughput serum and plasma proteomics that builds on ISO13485 standardisation and high-flow liquid chromatography to facilitate implementation in clinical laboratories and identifies 27 potential biomarkers that are differentially expressed depending on the WHO severity grade of COVID-19.
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Vitamin D is a regulator of endothelial nitric oxide synthase and arterial stiffness in mice.
Olena Andrukhova,Svetlana Slavic,Ute Zeitz,Sabine Riesen,Monika S. Heppelmann,Tamas Dezso Ambrisko,Mato Markovic,Wolfgang M. Kuebler,Reinhold G. Erben +8 more
TL;DR: The data demonstrate the importance of intact VDR signaling in the preservation of vascular function and may provide a mechanistic explanation for epidemiological data in humans showing that vitamin D insufficiency is associated with hypertension and endothelial dysfunction.
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Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury.
Jochen Grommes,Jean-Eric Alard,Maik Drechsler,Sarawuth Wantha,Matthias Mörgelin,Wolfgang M. Kuebler,Michael J. Jacobs,Philipp von Hundelshausen,Philipp Markart,Malgorzata Wygrecka,Klaus T. Preissner,Tilman M. Hackeng,Rory R. Koenen,Christian Weber,Oliver Soehnlein +14 more
TL;DR: A novel function of platelet-derived chemokine heteromers during ALI is identified and means for therapeutic interference are demonstrated, suggesting a sequential participation of platelets and neutrophils.
Journal ArticleDOI
Noninvasive measurement of regional cerebral blood flow by near-infrared spectroscopy and indocyanine green.
Wolfgang M. Kuebler,Axel Sckell,Oliver Habler,Martin Kleen,G. E. H. Kuhnle,Martin Welte,Konrad Messmer,Alwin E. Goetz +7 more
TL;DR: In this paper, a non-invasive technique for estimation of cerebral hemodynamics by use of near-infrared spectroscopy (NIRS) and an intravenously infused tracer dye is proposed.