Z
Zhong Zheng
Researcher at University of California, Los Angeles
Publications - 86
Citations - 2701
Zhong Zheng is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Medicine & Cellular differentiation. The author has an hindex of 25, co-authored 71 publications receiving 1934 citations. Previous affiliations of Zhong Zheng include University of California & Tsinghua University.
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Current development of biodegradable polymeric materials for biomedical applications
TL;DR: This review outlines the current development of biodegradable natural and synthetic polymeric materials for various biomedical applications, including tissue engineering, temporary implants, wound healing, and drug delivery.
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Effects of crystallization of polyhydroxyalkanoate blend on surface physicochemical properties and interactions with rabbit articular cartilage chondrocytes.
TL;DR: It was shown that the blend with a 1:1 ratio of PHB/PHBHHx possessed the highest surface free energy, which was the most optimal material for chondrocytes adhesion, and indicated that endochondral ossification of chondROcytes was remarkably influenced by the crystallinity of the polyesters.
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The antimicrobial and osteoinductive properties of silver nanoparticle/poly (dl-lactic-co-glycolic acid)-coated stainless steel
Yi Liu,Zhong Zheng,Janette N. Zara,Ching Yun Hsu,Donnalisa E. Soofer,Kevin S. Lee,Ronald K. Siu,Lloyd S. Miller,Xinli Zhang,Doug Carpenter,Chunling Wang,Kang Ting,Chia Soo +12 more
TL;DR: It is found that SNPSA exhibited strong antibacterial activity in vitro and ex vivo, and promoted MC3T3-E1 pre-osteoblasts proliferation and maturation in vitro, and induced osteogenesis while suppressing bacterial survival in contaminated rat femoral canals.
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Poly(hydroxybutyrate-co-hydroxyhexanoate) promoted production of extracellular matrix of articular cartilage chondrocytes in vitro.
TL;DR: Second-harmonic generation (SHG) imaging technique, combined with confocal fluorescence microscopy (CFM) revealed that PHBHHx in PHB scaffold provided better surface properties for anchoring type II collagen filaments and their penetration into internal layers of the scaffolds.
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The use of BMP-2 coupled – Nanosilver-PLGA composite grafts to induce bone repair in grossly infected segmental defects
Zhong Zheng,Wei Yin,Wei Yin,Janette N. Zara,Weiming Li,Weiming Li,Jinny Kwak,Rachna Mamidi,Min Lee,Ronald K. Siu,Richard Ngo,Joyce Wang,Doug Carpenter,Xinli Zhang,Benjamin M. Wu,Kang Ting,Chia Soo +16 more
TL;DR: It is demonstrated that metallic nanosilver particles (with a size of 20-40nm)-poly(lactic-co-glycolic acid) (PLGA) composite grafts have strong antibacterial properties, making it an ideal antimicrobial for bone regeneration in infected wounds.