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Chia Soo
Researcher at University of California, Los Angeles
Publications - 158
Citations - 8742
Chia Soo is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Bone regeneration & Mesenchymal stem cell. The author has an hindex of 51, co-authored 152 publications receiving 7363 citations. Previous affiliations of Chia Soo include University of California & University of Southern California.
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Journal ArticleDOI
A Review of the Clinical Side Effects of Bone Morphogenetic Protein-2
Aaron W. James,Gregory LaChaud,Jia Shen,Greg Asatrian,Vi Nguyen,Xinli Zhang,Kang Ting,Chia Soo +7 more
TL;DR: BMP-2 is a potent osteoinductive cytokine that has indeed revolutionized the bone graft substitute market; however, it simultaneously has accrued a worrisome side effect profile.
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Current development of biodegradable polymeric materials for biomedical applications
TL;DR: This review outlines the current development of biodegradable natural and synthetic polymeric materials for various biomedical applications, including tissue engineering, temporary implants, wound healing, and drug delivery.
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High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo.
Janette N. Zara,Ronald K. Siu,Xinli Zhang,Jia Shen,Richard Ngo,Min Lee,Weiming Li,Michael F. Chiang,Jonguk Chung,Jinny Kwak,Benjamin M. Wu,Kang Ting,Chia Soo +12 more
TL;DR: Overall, this study consistently reproduced BMP2 side effects of cyst-like bone and soft tissue swelling using high B MP2 concentration approaching the typical human 1500 μg/mL.
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Natural history of mesenchymal stem cells, from vessel walls to culture vessels
Iain R. Murray,Christopher C. West,Winters R. Hardy,Aaron W. James,Tea Soon Park,Alan Nguyen,Tulyapruek Tawonsawatruk,Lorenza Lazzari,Chia Soo,Bruno Péault,Bruno Péault +10 more
TL;DR: A growing body of experimental data is currently paving the way to the medical usage of autologous sorted perivascular cells for indications in which MSCs have been previously contemplated or actually used, such as bone regeneration and cardiovascular tissue repair.
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NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation
Jia Chang,Fei Liu,Min Lee,Benjamin M. Wu,Kang Ting,Janette N. Zara,Chia Soo,Khalid Al Hezaimi,Weiping Zou,Xiaohong Chen,David J. Mooney,Cun-Yu Wang +11 more
TL;DR: The results suggest that targeting IKK–NF-κB may have dual benefits in enhancing bone regeneration and repair and inhibiting inflammation, and this concept may also have applicability in many other tissue regeneration situations.