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Current development of biodegradable polymeric materials for biomedical applications

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TLDR
This review outlines the current development of biodegradable natural and synthetic polymeric materials for various biomedical applications, including tissue engineering, temporary implants, wound healing, and drug delivery.
Abstract
In the last half-century, the development of biodegradable polymeric materials for biomedical applications has advanced significantly. Biodegradable polymeric materials are favored in the development of therapeutic devices, including temporary implants and three-dimensional scaffolds for tissue engineering. Further advancements have occurred in the utilization of biodegradable polymeric materials for pharmacological applications such as delivery vehicles for controlled/sustained drug release. These applications require particular physicochemical, biological, and degradation properties of the materials to deliver effective therapy. As a result, a wide range of natural or synthetic polymers able to undergo hydrolytic or enzymatic degradation is being studied for biomedical applications. This review outlines the current development of biodegradable natural and synthetic polymeric materials for various biomedical applications, including tissue engineering, temporary implants, wound healing, and drug delivery.

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Journal ArticleDOI

A Comparative Review of Natural and Synthetic Biopolymer Composite Scaffolds.

TL;DR: An overview of various natural and synthetic polymers and their possible composite scaffolds with their physicochemical properties including biocompatibility, biodegradability, morphology, mechanical strength, pore size, and porosity are discussed in this article.
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Biodegradable Magnesium-Based Implants in Orthopedics-A General Review and Perspectives.

TL;DR: Progress made on the development of Mg‐based implants in basic, translational, and clinical research has laid down a foundation for developing a new era in the treatment of challenging and prevalent bone diseases.
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Fused deposition modeling-based additive manufacturing (3D printing): techniques for polymer material systems

TL;DR: A good overview of existing additive manufacturing techniques can be found in this paper, with more focus on the extrusion-based technologies (fused deposition modeling and direct ink writing) due to their scalability, cost efficiency and wider range of material processability.
Journal ArticleDOI

Prospects of biopolymer technology as an alternative option for non-degradable plastics and sustainable management of plastic wastes

TL;DR: In this article, a review of the prospects of biopolymer technology was emphasized to address the issues associated with non-degradability of plastics, and essential strategies were also discussed further for biopolymers as an alternative option for nondegradable plastics to help establish sustainable management plan for plastic wastes based on standards, certifications, and labeling.
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Natural composite dressings based on collagen, gelatin and plant bioactive compounds for wound healing: A review.

TL;DR: This review highlights the main characteristics and properties of a natural polymer, which is widely used as biomaterial, namely collagen and of its denatured form, gelatin, and applications of these composite biomaterials are discussed with emphasis on skin wound healing.
References
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Journal ArticleDOI

Alginate: properties and biomedical applications

TL;DR: This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.
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Biodegradable polymers as biomaterials

TL;DR: This review summarizes the main advances published over the last 15 years, outlining the synthesis, biodegradability and biomedical applications ofBiodegradable synthetic and natural polymers.
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Silk-based biomaterials

TL;DR: Studies with well-defined silkworm silk fibers and films suggest that the core silk fibroin fibers exhibit comparable biocompatibility in vitro and in vivo with other commonly used biomaterials such as polylactic acid and collagen.
Journal ArticleDOI

Chitosan chemistry and pharmaceutical perspectives.

TL;DR: Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. S. Nagar, Punjab-160 062, India, Institute of Biochemistry, Faculty of Medicine, Polytechnic University, Via Ranieri 67, IT-60100 Ancona, Italy, and Department of Medicinal Chemistry & Natural Products,The Hebrew University of Jerusalem, School of Pharmacy-Faculty of medicine, Jerusalem 91120, Israel.
Journal ArticleDOI

Collagens—structure, function, and biosynthesis

TL;DR: The importance of different collagen types not only for the understanding of collagen-related diseases, but also as a basis for the therapeutical use of members of this protein family discussed in other chapters of this issue is indicated.
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