Journal ArticleDOI
A review of micropumps
Daniel J. Laser,Juan G. Santiago +1 more
TLDR
In this article, the authors survey progress over the past 25 years in the development of microscale devices for pumping fluids and attempt to provide both a reference for micropump researchers and a resource for those outside the field who wish to identify the best micropumps for a particular application.Abstract:
We survey progress over the past 25 years in the development of microscale devices for pumping fluids. We attempt to provide both a reference for micropump researchers and a resource for those outside the field who wish to identify the best micropump for a particular application. Reciprocating displacement micropumps have been the subject of extensive research in both academia and the private sector and have been produced with a wide range of actuators, valve configurations and materials. Aperiodic displacement micropumps based on mechanisms such as localized phase change have been shown to be suitable for specialized applications. Electroosmotic micropumps exhibit favorable scaling and are promising for a variety of applications requiring high flow rates and pressures. Dynamic micropumps based on electrohydrodynamic and magnetohydrodynamic effects have also been developed. Much progress has been made, but with micropumps suitable for important applications still not available, this remains a fertile area for future research.read more
Citations
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Journal ArticleDOI
The origins and the future of microfluidics
TL;DR: The manipulation of fluids in channels with dimensions of tens of micrometres — microfluidics — has emerged as a distinct new field that has the potential to influence subject areas from chemical synthesis and biological analysis to optics and information technology.
Journal ArticleDOI
Microfluidics: Fluid physics at the nanoliter scale
Todd M. Squires,Stephen R. Quake +1 more
TL;DR: A review of the physics of small volumes (nanoliters) of fluids is presented, as parametrized by a series of dimensionless numbers expressing the relative importance of various physical phenomena as mentioned in this paper.
Journal ArticleDOI
Micromixers?a review
Nam-Trung Nguyen,Zhigang Wu +1 more
TL;DR: In this paper, the authors report the progress on the recent development of micromixers and present different types and designs of active and passive MCMs, as well as the operation points of the MCMs.
Journal ArticleDOI
Lab-on-a-chip: microfluidics in drug discovery.
Petra S. Dittrich,Andreas Manz +1 more
TL;DR: Current and future applications of microfluidics are reviewed and the potential of 'lab-on-a-chip' technology for drug discovery is highlighted.
Journal ArticleDOI
Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications
TL;DR: This critical review summarizes developments in microfluidic platforms that enable the miniaturization, integration, automation and parallelization of (bio-)chemical assays and attempts to provide a selection scheme based on key requirements of different applications and market segments.
References
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Journal ArticleDOI
Electric field mediated transport in nanometer diameter channels
TL;DR: Nanoporous polycarbonate nuclear-track-etched membranes were used to effect electric field modulation of the mass transport of cationic, anionic, and neutral species in aqueous buffer and the permeability response to electric fields depended on the molecular charge and electrolyte concentration.
Proceedings ArticleDOI
Electrically-activated, normally-closed diaphragm valves
TL;DR: In this paper, a closed diaphragm valve was designed to provide fully proportional control of flows in the range of 0-150 cm/sup 3/min at input pressures between 1 and 50 PSIG.
Patent
Micropump with improved priming
TL;DR: In this article, a micropump is machined to define an inlet valve (36), a pump chamber (34), and an outlet valve (48), which is then propelled along the wall on both sides of the part (60) by pushing the air away ahead of it and thus guaranteeing that no air bubble can be formed in the downstream compartment.
Proceedings ArticleDOI
A self-priming and bubble-tolerant piezoelectric silicon micropump for liquids and gases
TL;DR: In this paper, a piezoelectrically driven diaphragm actuator is combined with a valve unit consisting of two cantilever valves to achieve self-priming and bubble-tolerant operation.
Journal ArticleDOI
Integrated flow-regulated silicon micropump
TL;DR: In this article, a closed-loop controller is used to control the output flow of a piezoelectric silicon micropump with a controlled output flow, which can maintain a constant output flow when the pressure difference between the pump's output and input varies.