Clinical Assessment of Central Blood Pressure
TLDR
If central and peripheral pressure calibrations are equivalent, two major methods to estimate CBP—those based on generalized pressure transfer function or radial late systolic pressure—may be comparable in their accuracy of CBP parameter estimation.Abstract:
Central aortic blood pressure (CBP) is increasingly considered a better cardiovascular prognostic marker than conventional cuff brachial blood pressure. Because CBP cannot be directly measured noninvasively, it has to be estimated from peripheral pressure pulses. To assess estimated CBP appropriately, the accuracy and features of the estimation method should be considered. The aim of this review is to provide basic knowledge and information useful for interpreting and assessing estimated CBP from a methodological point of view. Precise peripheral pressure pulse recording has been enabled by the introduction of arterial applanation tonometry, for which the radial artery may be the optimal site. An automated tonometry device utilizing a sensor array is preferable in terms of reproducibility and objectivity. Calibration of a peripheral pressure waveform has unresolved problems for any estimation method, due to imperfect brachial sphygmomanometry. However, if central and peripheral pressure calibrations are equivalent, two major methods to estimate CBP—those based on generalized pressure transfer function or radial late systolic pressure—may be comparable in their accuracy of CBP parameter estimation.read more
Citations
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Journal ArticleDOI
Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness: A Scientific Statement From the American Heart Association
Raymond R. Townsend,Ian B. Wilkinson,Ernesto L. Schiffrin,Alberto Avolio,Julio A. Chirinos,John R. Cockcroft,Kevin S. Heffernan,Edward G. Lakatta,Carmel M. McEniery,Gary F. Mitchell,Samer S. Najjar,Wilmer W. Nichols,Elaine M. Urbina,Thomas Weber +13 more
TL;DR: The field of arterial stiffness investigation, which has exploded over the past 20 years, has proliferated without logistical guidance for clinical and research studies, and questions that remain to be addressed in this field are addressed.
Journal ArticleDOI
Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors
TL;DR: Typical values of cSBP and amplification in a healthy population and a population free of traditional CVRFs are now available according to age, sex, and brachial BP, providing values included from different devices with a wide geographical representation.
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Novel Methods for Pulse Wave Velocity Measurement
TL;DR: The great challenge is to explore the new instrumental solutions that allow the PWV assessment with fewer approximations for an accurately evaluation and relatively inexpensive techniques in order to be used in the clinical routine.
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Accuracy of commercial devices and methods for noninvasive estimation of aortic systolic blood pressure a systematic review and meta-analysis of invasive validation studies.
Theodore G. Papaioannou,Theofani D. Karageorgopoulou,Theodoros N. Sergentanis,Athanase D. Protogerou,Theodora Psaltopoulou,James E. Sharman,Thomas Weber,Jacques Blacher,Stella S. Daskalopoulou,Siegfried Wassertheurer,Ashraf W. Khir,Charalambos Vlachopoulos,Nikolaos Stergiopulos,Christodoulos Stefanadis,Wilmer W. Nichols,Dimitrios Tousoulis +15 more
TL;DR: Automated recording of waveforms, calibrated noninvasively by brachial mean arterial pressure/DBP values seems the most promising approach that can provide relatively more accurate, noninvasive estimation of a-SBP.
Journal ArticleDOI
A database of virtual healthy subjects to assess the accuracy of foot-to-foot pulse wave velocities for estimation of aortic stiffness
TL;DR: A database of virtual healthy subjects is created using a 1D model of the arterial hemodynamics and its application to central and peripheral foot-to-foot pulse wave velocities is presented.
References
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Journal ArticleDOI
Estimation of Central Aortic Pressure Waveform by Mathematical Transformation of Radial Tonometry Pressure Validation of Generalized Transfer Function
Chen Huan Chen,Erez Nevo,Barry J. Fetics,Peter H. Pak,Frank C.P. Yin,W L Maughan,David A. Kass +6 more
TL;DR: Central aortic pressures can be accurately estimated from radial tonometry with the use of a generalized TF, and the reconstructed waveform can provide arterial compliance estimates but may underestimate the augmentation index because the latter requires greater fidelity reproduction of the wave contour.
Journal ArticleDOI
Prospective Evaluation of a Method for Estimating Ascending Aortic Pressure From the Radial Artery Pressure Waveform
TL;DR: Aortic pressure pulse waves, generated from the radial pulse, showed agreement with the measured aortic pulse waves with respect to systolic, diastolic, pulse, and mean pressures, with mean differences <1 mm Hg.
Journal ArticleDOI
The influence of heart rate on augmentation index and central arterial pressure in humans
TL;DR: An inverse, linear relationship between AIx is demonstrated, likely due to alterations in the timing of the reflected pressure wave, produced by changes in the absolute duration of systole, which may explain the lack of rise in central systolic pressure during incremental pacing despite an increase in peripheral pressure.