Journal ArticleDOI
Complications from silicon-polymer intubulation of nerves.
TLDR
Since silicon‐polymer intubulation of nerve is now a proven model for producing chronic nerve compression, its use clinically may be contraindicated where neural regeneration is the desired goal.Abstract:
Three cases are reported to illustrate the potential danger of silicon-polymer intubulation of nerve for either nerve repair or following neurolysis Since silicon-polymer intubulation of nerve is now a proven model for producing chronic nerve compression, its use clinically may be contraindicated where neural regeneration is the desired goalread more
Citations
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Journal ArticleDOI
Host response to tissue engineered devices
TL;DR: The inflammatory response to the biomaterial component and immune response towards transplanted cells are described and examples of devices appropriately integrated as assessed morphologically with the host for various applications including bone, nerve, and skin regeneration are illustrated.
Journal ArticleDOI
Construction of tissue engineered nerve grafts and their application in peripheral nerve regeneration
TL;DR: Different nerve grafts used for peripheral nerve repair are summarized, various basic components of tissue engineered nerve grafting are highlighted in terms of their structures, features, and nerve regeneration-promoting actions, and current clinical applications and future perspectives are discussed.
Journal ArticleDOI
Repairing injured peripheral nerves: Bridging the gap
Ronald Deumens,Ahmet Bozkurt,Marcel F Meek,Marco A. E. Marcus,Marco A. E. Marcus,Elbert A.J. Joosten,Elbert A.J. Joosten,Joachim Weis,Joachim Weis,Gary A. Brook,Gary A. Brook +10 more
TL;DR: The developments in bridging technology which aim to replace the autograft are described, which are of utmost importance to develop and optimise treatments of the most challenging peripheral nerve injuries.
Journal ArticleDOI
A polymer foam conduit seeded with Schwann cells promotes guided peripheral nerve regeneration.
TL;DR: A novel, fully biodegradable polymer conduit was designed and fabricated for use in peripheral nerve repair, which approximates the macro- and microarchitecture of native peripheral nerves and provides an environment permissive to axonal regeneration.
Journal ArticleDOI
Peripheral nerve regeneration through guidance tubes.
TL;DR: This review focuses on artificial conduits, nerve regeneration through them, and an account of various synthetic materials that comprise these tubes in experimental animal and clinical trials.
References
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Journal ArticleDOI
An alternative to the classical nerve graft for the management of the short nerve gap.
TL;DR: It is demonstrated that the primate peripheral nerve can regenerate across short nerve gaps when guided by an appropriate nerve conduit, suggesting that a single-stage biodegradable polyglycolic acid conduit may be used as an alternative to a short interfascicular nerve graft.
Journal ArticleDOI
Chronic nerve compression--an experimental model in the rat.
TL;DR: This model of chronic nerve compression of adult male Sprague Dawley rats appears to be a valid one with which to study other aspects of both the pathophysiology and treatment of Chronic nerve compression.
Journal ArticleDOI
Nerve regeneration across an extended gap: A neurobiological view of nerve repair and the possible involvement of neuronotrophic factors
Göran Lundborg,Lars-Bertil Dahlin,Nils Danielsen,Hans-Arne Hansson,Ann Johannesson,Frank M. Longo,Silvio Varon +6 more
TL;DR: The results suggest that if the regrowing proximal stump is in an appropriate environment, it can form a well organized and oriented nerve trunk, which may also support nerve regeneration in vivo.
Journal ArticleDOI
A primate model for chronic nerve compression.
TL;DR: This model is expanded to the multifascicular median nerve of the cynomolgus monkey to test whether or not current surgical treatment modalities for nerve entrapment will alter the course of chronic nerve compression, and there did not appear to be a difference between nerves treated by decompression alone or by decomression and internal neurolysis.
Journal ArticleDOI
Artificial tendons. early development and application.
TL;DR: Results show that this artificial tendon functions successfully as a temporary replacement while a new tendon sheath develops, producing an excellent gliding canal, making it possible to salvage tendon motion through scar tissue.
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Clinical nerve reconstruction with a bioabsorbable polyglycolic acid tube
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