Journal ArticleDOI
Extracorporeal circulation in neonatal respiratory failure: A prospective randomized study
TLDR
A prospective controlled randomized study of the use of extracorporeal membrane oxygenation to treat newborns with respiratory failure using the "randomized play-the-winner" statistical method, which allows lung rest and improves survival compared to conventional ventilator therapy in newborn infants with severe respiratory failure.About:
This article is published in Journal of Critical Care.The article was published on 1987-03-01. It has received 549 citations till now. The article focuses on the topics: Extracorporeal circulation.read more
Citations
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Journal ArticleDOI
Analysis of homogeneity of treatment effect in adaptive multicenter clinical trials
Li Chen,Roy N. Tamura +1 more
TL;DR: An exact test for analyzing the homogeneity of treatment effect in adaptive multicenter clinical trials is proposed and should be used to incorporate the adaptive nature of the design.
Journal ArticleDOI
The Extracorporeal Membrane Oxygenation Wish
TL;DR: Since 1976, when Bartlett and coworkers 1 first described four of 14 surviving pediatric patients treated with ECMO, there has been a slow, but increasing, movement to embrace this technology.
Book ChapterDOI
The Story of ECLS: History and Future
J. Ann Morris,Robert Pollock,Brittany A. Zwischenberger,Cherry Ballard-Croft,Joseph B. Zwischenberger +4 more
TL;DR: ECMO currently serves as a form of life support for critically ill patients when traditional supportive care is no longer effective, and has also become a bridge to transplantation and a way to manage acute shock.
Journal ArticleDOI
Extracorporeal membrane oxygenation and pediatric cardiology
Book ChapterDOI
Adaptive Trial Designs
TL;DR: The nature of any experiment is that its outcome is uncertain, and the parameters required to design the trial cannot be known for certain, and there is no guarantee that the design is optimal.