Platelet-rich fibrin: Evolution of a second-generation platelet concentrate
Reads0
Chats0
TLDR
The evolution of this novel platelet concentrate, referred to as PRF, is described, which has been shown to have several advantages over traditionally prepared PRP, including ease of preparation and lack of biochemical handling of blood.Abstract:
Platelet-rich plasma (PRP) is a platelet concentrate that has been used widely to accelerate soft-tissue and hard-tissue healing. The preparation of PRP has been described by several authors. Platelet-rich fibrin (PRF) was first described by Choukroun et al. in France. It has been referred to as a second-generation platelet concentrate, which has been shown to have several advantages over traditionally prepared PRP. Its chief advantages include ease of preparation and lack of biochemical handling of blood, which makes this preparation strictly autologous. This article describes the evolution of this novel platelet concentrate, referred to as PRF.read more
Citations
More filters
Journal ArticleDOI
Advancing biomaterials of human origin for tissue engineering
Fa-Ming Chen,Xiaohua Liu +1 more
TL;DR: An exploration of the structural, mechanical, biochemical and biological information present in native human tissue for bioengineering applications is focused on to provide inspiration for the design of future biomaterials.
Journal ArticleDOI
Principles and Methods of Preparation of Platelet-Rich Plasma: A Review and Author's Perspective.
Dhurat R,M. S. Sukesh +1 more
TL;DR: The principles and preparation methods of PRP are reviewed based on available literature and a perspective in standardizing a safe, simple protocol that can be followed to obtain an optimal consistent platelet yield is placed.
Journal ArticleDOI
Slow release of growth factors and thrombospondin-1 in Choukroun's platelet-rich fibrin (PRF): a gold standard to achieve for all surgical platelet concentrates technologies.
TL;DR: Choukroun's platelet-rich fibrin (PRF) is a second generation platelet concentrate that releases high quantities of three main growth factors, including TGFβ-1, platelet derived growth factor AB, PDGF-AB and an important coagulation matricellular glycoprotein during 7 days.
Journal ArticleDOI
Comparative release of growth factors from PRP, PRF, and advanced-PRF
Eizaburo Kobayashi,Laura Flückiger,Masako Fujioka-Kobayashi,Masako Fujioka-Kobayashi,Kosaku Sawada,Kosaku Sawada,Anton Sculean,Benoit Schaller,Richard J. Miron +8 more
TL;DR: PRP can be recommended for fast delivery of growth factors whereas A-PRF is better-suited for long-term release, according to the results of the present study.
Journal ArticleDOI
In vitro effects of Choukroun's PRF (platelet-rich fibrin) on human gingival fibroblasts, dermal prekeratinocytes, preadipocytes, and maxillofacial osteoblasts in primary cultures
David M. Dohan Ehrenfest,Antoine Diss,Guillaume Odin,Pierre Doglioli,Marie-Pascale Hippolyte,Jean-Baptiste Charrier +5 more
TL;DR: Analysis of osteoblast cultures in differentiation conditions with PRF revealed a starting mineralization process in the PRF membrane itself after 14 days, which could be the source of differential geographic regulation within the culture and explain the double contradictory effect proliferation/differentiation observed on osteoblasts.