Journal ArticleDOI
Review of the biology of quercetin and related bioflavonoids
J.V. Formica,W. Regelson +1 more
TLDR
The role of flavonoids may transcend their presence in food as mentioned in this paper, however, the amount of quercetin that remains biologically available may not be of sufficient concentration, theoretically, to explain the beneficial effects seen with the Mediterranean diet.Citations
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The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds.
Martin van den Berg,Linda S. Birnbaum,Michael S. Denison,Mike De Vito,William H. Farland,Mark Feeley,Heidelore Fiedler,Helen Håkansson,Annika Hanberg,Laurie C. Haws,Martin Rose,Stephen Safe,Dieter Schrenk,Chiharu Tohyama,Angelika Tritscher,Jouko Tuomisto,Mats Tysklind,Nigel J. Walker,Richard E. Peterson +18 more
TL;DR: Concern was expressed about direct application of the TEF/total toxic equivalency (TEQ) approach to abiotic matrices, such as soil, sediment, etc., for direct application in human risk assessment as the present TEF scheme and TEQ methodology are primarily intended for estimating exposure and risks via oral ingestion.
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Flavonoids: a review of probable mechanisms of action and potential applications
Robert J. Nijveldt,Els Van Nood,Danny E. C. van Hoorn,Petra G. Boelens,Klaske van Norren,Paul A. M. van Leeuwen +5 more
TL;DR: The aim of this review, a summary of the putative biological actions of flavonoids, was to obtain a further understanding of the reported beneficial health effects of these substances.
Journal ArticleDOI
Expanding the utilization of sustainable plant products in aquafeeds: a review
Delbert M. Gatlin,Frederic T. Barrows,Paul B. Brown,Konrad Dabrowski,T. Gibson Gaylord,Ronald W. Hardy,Eliot M. Herman,Gongshe Hu,Åshild Krogdahl,Richard Nelson,Kenneth E. Overturf,Michael B. Rust,Wendy M. Sealey,Denise I. Skonberg,Edward Souza,David A.J. Stone,Rich Wilson,Eve Syrkin Wurtele +17 more
TL;DR: This document reviews various plant feedstuis, which currently are or potentially may be incorporated into aquafeeds to support the sustainable production of various ¢sh species in aquaculture and strategies and techniques to optimize the nutritional composition and limit potentially adverse eiects of bioactive compounds are described.
Journal ArticleDOI
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals.
Michael S. Denison,Scott R. Nagy +1 more
TL;DR: Evidence for the structural promiscuity of AhR ligand binding is described and the current state of knowledge with regards to the activation of the AhR signaling pathway by naturally occurring exogenous and endogenous ligands is discussed.
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Antioxidant activity of food constituents: an overview
TL;DR: The most commonly methods used in vitro determination of antioxidant capacity of food constituents are reviewed and presented, and the general chemistry underlying the assays in the present paper was clarified.
References
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Journal ArticleDOI
Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test
TL;DR: The methods described include the standard plate test, the use and storage of the bacterial tester strains, preparation and use of the liver homogenates, and the methods of inducing the rats for elevated microsomal enzyme activity.
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Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study.
TL;DR: Flavonoids in regularly consumed foods may reduce the risk of death from coronary heart disease in elderly men and showed an inverse relation with incidence of myocardial infarction.
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Nitric oxide as a secretory product of mammalian cells.
TL;DR: How different forms of nitric oxide synthase help confer specificity and diversity on the effects of this remarkable signaling molecule is reviewed.
Journal ArticleDOI
Wine, alcohol, platelets, and the French paradox for coronary heart disease
Serge Renaud,M de Lorgeril +1 more
TL;DR: Data from Caerphilly, Wales, show that platelet aggregation, which is related to CHD, is inhibited significantly by alcohol at levels of intake associated with reduced risk of CHD.
Journal ArticleDOI
Endothelium-derived relaxing and contracting factors.
TL;DR: Endothelium-dependent relaxation of blood vessels is produced by a large number of agents (e.g., acetylcholine, ATP and ADP, substance P, bradykinin, histamine, thrombin, serotonin). With some agents, relaxation may be limited to certain species and/or blood vessels as mentioned in this paper.