The Anal Pap Smear: Cytomorphology of squamous intraepithelial lesions.
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TLDR
Liquid based anal smears had a high sensitivity for detection of ASIL but a low specificity for predicting the severity of the abnormality in subsequent biopsy, suggesting that all patients with a diagnosis of ASC-US and above be recommended for high resolution anoscopy with biopsy.Abstract:
Anal smears are increasingly being used as a screening test for anal squamous intraepithelial lesions (ASILs). This study was undertaken to assess the usefulness and limitations of anal smears in screening for ASILs.read more
Citations
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Journal ArticleDOI
Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis
Dorothy A Machalek,Mary Poynten,Fengyi Jin,Christopher K Fairley,Annabelle Farnsworth,Suzanne M. Garland,Suzanne M. Garland,Suzanne M. Garland,Richard J. Hillman,Richard J. Hillman,Kathy Petoumenos,Jennifer M. Roberts,Sepehr N. Tabrizi,Sepehr N. Tabrizi,Sepehr N. Tabrizi,David J Templeton,David J Templeton,Andrew E. Grulich +17 more
TL;DR: In this paper, the authors search PubMed, OVID Medline, and Embase for all studies published before Nov 1, 2011, that reported prevalence and incidence of anal HPV detection, intraepithelial neoplasia (AIN), and anal cancer in MSM.
Book ChapterDOI
The Bethesda System for Reporting Cervical Cytology
TL;DR: The Bethesda system (TBS) is a system for reporting cervical or vaginal cytologic diagnoses, used for reporting Pap smear results, and was introduced in 1988 and revised in 1991, 2001, and 2014.
Journal ArticleDOI
Screening HIV-infected individuals for anal cancer precursor lesions: a systematic review.
Elizabeth Y. Chiao,Elizabeth Y. Chiao,Thomas P. Giordano,Thomas P. Giordano,Joel M. Palefsky,Stephen K. Tyring,Hashem B. El–Serag,Hashem B. El–Serag +7 more
TL;DR: A systematic review of the indirect evidence regarding the utility of anal Papanicolau (Pap) smear screening of HIV-infected individuals in the highly active antiretroviral therapy era identifies important areas for further study before routine anal Pap smear screening can be recommended.
Journal ArticleDOI
Anal cancer and cervical cancer screening: Key differences
TL;DR: An overview of anal cancer screening is provided while highlighting its differences from cervical cancer screening and the remaining obstacles and controversies to implementation of a successful anus cancer screening program.
Journal ArticleDOI
Practice parameters for anal squamous neoplasms.
Phillip Fleshner,Sridhar Chalasani,George J. Chang,David H. Levien,Neil Hyman,W. Donald Buie,Rectal Surgeons +6 more
TL;DR: Practice parameters for Anal Squamous Neoplasms and Diseases of the Colon & Rectum are described.
References
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Journal ArticleDOI
The 2001 Bethesda System: terminology for reporting results of cervical cytology.
Diane Solomon,Diane D. Davey,Robert J. Kurman,Marianne U. Prey,Stephen S. Raab,Mark E. Sherman,David C. Wilbur,Nancy A. Young +7 more
TL;DR: The 2001 Bethesda System terminology reflects important advances in biological understanding of cervical neoplasia and cervical screening technology.
Journal ArticleDOI
2001 Consensus Guidelines for the Management of Women With Cervical Cytological Abnormalities
TL;DR: Management of women with atypical squamous cells (ASC) depends on whether the Papanicolaou test is subcategorized as of undetermined significance (ASC-US) or as cannot exclude high-grade squamous intraepithelial lesion (HSIL) (asc-H).
Journal ArticleDOI
Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer
Janet R. Daling,Janet R. Daling,Margaret M. Madeleine,Margaret M. Madeleine,Lisa G. Johnson,Stephen M. Schwartz,Stephen M. Schwartz,A B A Katherine Shera,Michelle A. Wurscher,Joseph J. Carter,Peggy L. Porter,Peggy L. Porter,Denise A. Galloway,Denise A. Galloway,James K. McDougall,James K. McDougall +15 more
TL;DR: A population‐based case–control study of anal cancer to examine factors that may account for this increase in incidence among both men and women since 1973.
Journal ArticleDOI
Spectrum of AIDS-associated malignant disorders
James J. Goedert,Timothy R. Coté,Phillip Virgo,Steven M. Scoppa,Douglas W. Kingma,Mitchell H. Gail,Elaine S. Jaffe,Robert J. Biggar +7 more
TL;DR: Data indicate that AIDS leads to a significantly increased risk of Hodgkin's disease, multiple myeloma, brain cancer, and seminoma, and Immunological failure to control herpes or other viral infections may contribute to these malignant diseases.
Journal ArticleDOI
The clinical effectiveness and cost-effectiveness of screening for anal squamous intraepithelial lesions in homosexual and bisexual HIV-positive men.
Sue J. Goldie,Karen M. Kuntz,Milton C. Weinstein,Kenneth A. Freedberg,Mark L. Welton,Joel M. Palefsky +5 more
TL;DR: Screening HIV-positive homosexual and bisexual men for ASIL and anal SCC with anal Pap tests offers quality-adjusted life expectancy benefits at a cost comparable with other accepted clinical preventive interventions.