Journal ArticleDOI
Validation of the National Health Insurance Research Database with ischemic stroke cases in Taiwan.
TLDR
The National Health Insurance Research Database (NHIRD) is commonly used for pharmacoepidemiological research in Taiwan and the validity of the database for patients with a principal diagnosis of ischemic stroke is evaluated.Abstract:
Objective
The National Health Insurance Research Database (NHIRD) is commonly used for pharmacoepidemiological research in Taiwan. This study evaluated the validity of the database for patients with a principal diagnosis of ischemic stroke.
Study design and methods
This cross-sectional study compares records in the NHIRD with those in one medical center. Patients hospitalized for ischemic stroke in 1999 were identified from both databases. The discharge notes, laboratory data, and medication orders during admission and the first discharge visit were reviewed to validate ischemic stroke diagnoses and aspirin prescribing in the NHIRD. Agreement between the two databases in comorbidities of ischemic stroke diagnosis was evaluated using ICD-9 codes.
Results
Three hundred and seventy two cases were identified from the NHIRD; among them, 364 cases (97.85%) were confirmed as ischemic stroke by radiology examination and clinical presentation. Among these confirmed cases, 344 (94.51%) were assigned ‘ischemic stroke’ as the principal diagnosis in the NHIRD. The overall agreement of comorbid diagnoses between the databases was 48.39%. The PPV for selected conditions also varied widely, from 0.50 for fracture to 1.00 for colon cancer. The accuracy of recorded aspirin prescriptions was higher in first post-discharge visits (PPV = 0.94) than during hospitalization (PPV = 0.88).
Conclusion
The accuracy of the NHIRD in recording ischemic stroke diagnoses and aspirin prescriptions was high, and the NHIRD appears to be a valid resource for population research in ischemic stroke. Copyright © 2010 John Wiley & Sons, Ltd.read more
Citations
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Journal ArticleDOI
Association between nucleoside analogues and risk of hepatitis B virus-related hepatocellular carcinoma recurrence following liver resection
Chun Ying Wu,Yi Ju Chen,Hsiu J. Ho,Yao-Chun Hsu,Yao-Chun Hsu,Ken N. Kuo,Ming-Shiang Wu,Jaw-Town Lin,Jaw-Town Lin,Jaw-Town Lin +9 more
TL;DR: Nucleoside analogue use was associated with a lower risk of HCC recurrence among patients with HBV-related HCC after liver resection, and this association was verified in all subgroups of patients.
Journal ArticleDOI
Taiwan's National Health Insurance Research Database: past and future.
Cheng Yang Hsieh,Chien Chou Su,Shih Chieh Shao,Shih Chieh Shao,Sheng-Feng Sung,Swu Jane Lin,Yea Huei Kao Yang,Edward Chia Cheng Lai +7 more
TL;DR: It is believed that NHIRD with multiple data sources could represent a powerful research engine with enriched dimensions and could serve as a guiding light for real-world evidence-based medicine in Taiwan.
Journal ArticleDOI
Validation of acute myocardial infarction cases in the national health insurance research database in taiwan.
TL;DR: The NHIRD appears to be a valid resource for population research in cardiovascular diseases by cross-comparisons of discharge diagnoses listed in the NHIRD with those in the medical records obtained from a medical center in Taiwan.
Journal ArticleDOI
Validating the diagnosis of acute ischemic stroke in a National Health Insurance claims database
TL;DR: Using five-digit ICD-9 codes to identify AIS cases will markedly decrease the false-positive rate compared with using the commonly used three-digit method.
Journal ArticleDOI
Validity of Diagnostic Codes for Acute Stroke in Administrative Databases: A Systematic Review.
TL;DR: While most cases of prevalent cerebrovascular disease can be detected using 430-438/I60-I69 collectively, acute stroke must be defined using more specific codes, and linking vital statistics and hospitalization data may improve the ascertainment of fatal stroke.
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