A
Alan Solomon
Researcher at University of Tennessee
Publications - 115
Citations - 5406
Alan Solomon is an academic researcher from University of Tennessee. The author has contributed to research in topics: Amyloid & Amyloidosis. The author has an hindex of 36, co-authored 115 publications receiving 4955 citations. Previous affiliations of Alan Solomon include University Of Tennessee System.
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Journal ArticleDOI
Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): A consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis
Morie A. Gertz,Raymond L. Comenzo,Rodney H. Falk,Jean Paul Fermand,Bouke P. C. Hazenberg,Philip N. Hawkins,Giampaolo Merlini,Philippe Moreau,Pierre Ronco,Vaishali Sanchorawala,Orhan Sezer,Alan Solomon,Giles Grateau +12 more
TL;DR: A consensus panel was convened comprising 13 specialists actively involved in the treatment of patients with amyloidosis, and a consensus was developed defining each organ involved and the criteria for response.
Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): a consensus opinion from th 10th International Symposium on Amyloid an Amyloidosis, Tours, France, 18-22 April 2004
IT Istituto Superiore di Sanit,G. Grateau,Alan Solomon,O. Sezer,Sanchorawala,Pierre Ronco,Philippe Moreau,Merlini G,Philip N. Hawkins,Hazenberg Bp,Fermand Jp,Rodney H. Falk,Raymond L. Comenzo,Gertz Ma +13 more
Journal ArticleDOI
Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis
Raymond L. Comenzo,Donna E. Reece,Giovanni Palladini,David C. Seldin,Vaishali Sanchorawala,Heather Landau,Rodney H. Falk,Karen Wells,Alan Solomon,Ashutosh D. Wechalekar,Jeffrey A. Zonder,Angela Dispenzieri,Morie A. Gertz,Howard Streicher,Martha Skinner,Robert A. Kyle,Giampaolo Merlini +16 more
TL;DR: This manuscript provides a framework for the design and conduct of systematic collaborative clinical research in AL to encourage more rapid testing of therapies and to expedite new drug development and approval.
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Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology.
Joakim Bergström,Åsa Gustavsson,Ulf Hellman,Knut Sletten,Charles L. Murphy,Deborah T. Weiss,Alan Solomon,Bert Ove Olofsson,Per Westermark +8 more
TL;DR: Detailed morphological, histochemical, immunological, and structural analyses of specimens obtained from 14 individuals with SSA and 11 Swedish FAP patients provide substantive evidence for the morphological and structural heterogeneity of TTR fibrils and suggest that the two types of deposition may reflect fundamental differences in the pathogenesis of the TTR‐associated amyloidoses.
Journal ArticleDOI
Antibody-Mediated Resolution of Light Chain-Associated Amyloid Deposits
Rudi Hrncic,Jonathan S. Wall,Dennis Wolfenbarger,Charles L. Murphy,Maria Schell,Deborah T. Weiss,Alan Solomon +6 more
TL;DR: The demonstration that AL amyloid resolution can be induced by passive administration of an amylid-reactive antibody has potential clinical benefit in the treatment of patients with primary amyloidsosis and other acquired or inherited amyloidal-associated disorders.