R
Raymond L. Comenzo
Researcher at Tufts Medical Center
Publications - 285
Citations - 15560
Raymond L. Comenzo is an academic researcher from Tufts Medical Center. The author has contributed to research in topics: AL amyloidosis & Amyloidosis. The author has an hindex of 55, co-authored 263 publications receiving 13847 citations. Previous affiliations of Raymond L. Comenzo include Boston Medical Center & Kettering University.
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Journal ArticleDOI
Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): A consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis
Morie A. Gertz,Raymond L. Comenzo,Rodney H. Falk,Jean Paul Fermand,Bouke P. C. Hazenberg,Philip N. Hawkins,Giampaolo Merlini,Philippe Moreau,Pierre Ronco,Vaishali Sanchorawala,Orhan Sezer,Alan Solomon,Giles Grateau +12 more
TL;DR: A consensus panel was convened comprising 13 specialists actively involved in the treatment of patients with amyloidosis, and a consensus was developed defining each organ involved and the criteria for response.
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The Systemic Amyloidoses
TL;DR: Amyloidosis is not a single disease but a term for diseases that share a common feature: the extracellular deposition of pathologic insoluble fibrillar proteins in organs and tissues.
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New Criteria for Response to Treatment in Immunoglobulin Light Chain Amyloidosis Based on Free Light Chain Measurement and Cardiac Biomarkers: Impact on Survival Outcomes
Giovanni Palladini,Angela Dispenzieri,Morie A. Gertz,Shaji Kumar,Ashutosh D. Wechalekar,Philip N. Hawkins,Stefan Schönland,Ute Hegenbart,Raymond L. Comenzo,Efstathios Kastritis,Meletios A. Dimopoulos,Arnaud Jaccard,Catherine Klersy,Giampaolo Merlini +13 more
TL;DR: This study identifies and validates new criteria for response to first-line treatment in AL amyloidosis, based on their association with survival in large patient populations, and offers surrogate end points for clinical trials.
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International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders
Angela Dispenzieri,Robert A. Kyle,Giampaolo Merlini,Jesús F. San Miguel,Heinz Ludwig,Roman Hájek,Antonio Palumbo,Sundar Jagannath,J. Bladé,Sagar Lonial,Meletios A. Dimopoulos,Raymond L. Comenzo,H. Einsele,Bart Barlogie,KC Anderson,Morie A. Gertz,J L Harousseau,M. Attal,Patrizia Tosi,Pieter Sonneveld,Mario Boccadoro,Gareth J. Morgan,Paul G. Richardson,O. Sezer,Maria-Victoria Mateos,Michele Cavo,Douglas E. Joshua,Ingemar Turesson,Wenming Chen,K. Shimizu,R. L. Powles,S V Rajkumar,Brian G.M. Durie +32 more
TL;DR: Consensus guidelines for the use of the serum immunoglobulin-free light chain assay are provided, in the diagnosis and management of clonal PCD.
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International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma.
Meletios A. Dimopoulos,Evangelos Terpos,Raymond L. Comenzo,Patrizia Tosi,Meral Beksac,Orhan Sezer,David S. Siegel,Henk M. Lokhorst,Shaji Kumar,S V Rajkumar,Ruben Niesvizky,Lia A. Moulopoulos,Brian G.M. Durie +12 more
TL;DR: Bone scintigraphy has no place in the routine staging of myeloma, whereas sequential dual-energy X-ray absorptiometry scans are not recommended, and Positron emission tomography/CT or MIBI imaging are also not recommended for routine use in the management of Myeloma patients.