A
Alexander I. Archakov
Researcher at Russian National Research Medical University
Publications - 423
Citations - 8512
Alexander I. Archakov is an academic researcher from Russian National Research Medical University. The author has contributed to research in topics: Cytochrome & Proteome. The author has an hindex of 40, co-authored 403 publications receiving 7703 citations. Previous affiliations of Alexander I. Archakov include Russian Academy & Academy of Medical Sciences, United Kingdom.
Papers
More filters
Journal ArticleDOI
Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database.
Gilbert S. Omenn,David J. States,Marcin Adamski,Thomas W. Blackwell,Rajasree Menon,Henning Hermjakob,Rolf Apweiler,Brian B. Haab,Richard J. Simpson,James S. Eddes,Eugene A. Kapp,Robert L. Moritz,Daniel W. Chan,Alex J. Rai,Arie Admon,Ruedi Aebersold,Ruedi Aebersold,Jimmy K. Eng,William S. Hancock,Stanley A. Hefta,Helmut E. Meyer,Young Ki Paik,Jong Shin Yoo,Peipei Ping,Joel G. Pounds,Joshua N. Adkins,Xiaohong Qian,Rong Wang,Valerie C. Wasinger,Chi Yue Wu,Xiaohang Zhao,Rong Zeng,Alexander I. Archakov,Akira Tsugita,Ilan Beer,Akhilesh Pandey,Michael Pisano,Philip C. Andrews,Harald Tammen,David W. Speicher,Samir M. Hanash,Samir M. Hanash +41 more
TL;DR: Reverse protein to DNA matching identified proteins for 118 previously unidentified ORFs in the PPP database, and the database permits examination of many other subsets, such as 1274 proteins identified with three or more peptides.
Journal ArticleDOI
The human proteome project: Current state and future direction
Pierre Legrain,Ruedi Aebersold,Ruedi Aebersold,Alexander I. Archakov,Amos Marc Bairoch,Kumar Bala,Laura Beretta,John J.M. Bergeron,Christoph H. Borchers,Garry L. Corthals,Catherine E. Costello,Eric W. Deutsch,Bruno Domon,William S. Hancock,Fuchu He,Denis F. Hochstrasser,György Marko-Varga,Ghasem Hosseini Salekdeh,Salvatore Sechi,Michael Snyder,Sudhir Srivastava,Mathias Uhlén,Cathy H. Wu,Tadashi Yamamoto,Young Ki Paik,Gilbert S. Omenn +25 more
TL;DR: The Human Proteome Organization urges each national research funding agency and the scientific community at large to identify their preferred pathways to participate in aspects of this highly promising project in a HPP consortium of funders and investigators.
Journal ArticleDOI
The Size of the Human Proteome: The Width and Depth.
Elena A. Ponomarenko,Ekaterina V. Poverennaya,Ekaterina V. Ilgisonis,Mikhail A. Pyatnitskiy,Arthur T. Kopylov,Victor G. Zgoda,Andrey Lisitsa,Alexander I. Archakov +7 more
TL;DR: In this article, meta-analysis of neXtProt knowledge base is proposed for theoretical prediction of the number of different proteoforms that arise from alternative splicing (AS), single amino acid polymorphisms (SAPs), and posttranslational modifications (PTMs).
Journal ArticleDOI
Protein-protein interactions as a target for drugs in proteomics
Alexander I. Archakov,Vadim M. Govorun,Alexander V. Dubanov,Yuri D. Ivanov,Alexander V. Veselovsky,Paul J. Lewi,Paul A. J. Janssen +6 more
TL;DR: This review highlights the methods of bioinformatics and functional proteomics of protein‐protein interaction investigation, and the contact surfaces of temporary protein complexes have unique structure and properties and they represent prospective targets for a new generation of drugs.
Journal ArticleDOI
Standard guidelines for the chromosome-centric human proteome project
Young Ki Paik,Gilbert S. Omenn,Mathias Uhlén,Samir M. Hanash,György Marko-Varga,Ruedi Aebersold,Amos Marc Bairoch,Tadashi Yamamoto,Pierre Legrain,Hyoung Joo Lee,Keun Na,Seul Ki Jeong,Fuchu He,Pierre-Alain Binz,Toshihide Nishimura,Paul Keown,Mark S. Baker,Jong Shin Yoo,Jérôme Garin,Alexander I. Archakov,John J.M. Bergeron,Ghasem Hosseini Salekdeh,William S. Hancock,William S. Hancock +23 more
TL;DR: Standard guidelines set out the collaborative consensus of the C-HPP teams, introduce topics associated with experimental approaches, data production, quality control, treatment, and transparency of data, governance of the consortium, and collaborative benefits, and facilitate the goal of a comprehensive analysis of the human proteome.