V
Victor G. Zgoda
Researcher at Russian Academy
Publications - 133
Citations - 1980
Victor G. Zgoda is an academic researcher from Russian Academy. The author has contributed to research in topics: Proteome & Medicine. The author has an hindex of 21, co-authored 111 publications receiving 1531 citations.
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Journal ArticleDOI
The Size of the Human Proteome: The Width and Depth.
Elena A. Ponomarenko,Ekaterina V. Poverennaya,Ekaterina V. Ilgisonis,Mikhail A. Pyatnitskiy,Arthur T. Kopylov,Victor G. Zgoda,Andrey Lisitsa,Alexander I. Archakov +7 more
TL;DR: In this article, meta-analysis of neXtProt knowledge base is proposed for theoretical prediction of the number of different proteoforms that arise from alternative splicing (AS), single amino acid polymorphisms (SAPs), and posttranslational modifications (PTMs).
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Ovarian cancer marker of 11.7 kDa detected by proteomics is a serum amyloid A1
Sergei A. Moshkovskii,Marina V. Serebryakova,Konstantin B. Kuteykin-Teplyakov,O. V. Tikhonova,E. I. Goufman,Victor G. Zgoda,Irina N. Taranets,Oleg V. Makarov,Alexander I. Archakov +8 more
TL;DR: To reduce the number of major plasma components, thermostable plasma fractions were examined to search for a biomarker of ovarian cancer and an apparent cancer biomarker was detected in these fractions using ProteinChip SELDI‐TOF mass spectrometry system.
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AFM fishing nanotechnology is the way to reverse the Avogadro number in proteomics.
TL;DR: In cases where the fishing becomes irreversible, its combination with an AFM detector enables the registration of single protein molecules, and that opens up a way to lower the CSL down to the reverse Avogadro number.
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Biospecific irreversible fishing coupled with atomic force microscopy for detection of extremely low‐abundant proteins
TL;DR: The proposed method, which combines biospecific fishing with AFM, allowed us to attain DL values of 10−11 M under reversible binding conditions and 10−16‽M under irreversible binding conditions.
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Two-dimensional electrophoretic proteome study of serum thermostable fraction from patients with various tumor conditions.
E. I. Goufman,Sergei A. Moshkovskii,O. V. Tikhonova,Petr G. Lokhov,Victor G. Zgoda,Marina V. Serebryakova,I. Yu. Toropygin,M. A. Vlasova,M. R. Safarova,Oleg V. Makarov,Alexander I. Archakov +10 more
TL;DR: The thermostable fraction of serum samples from patients with ovarian, uterus, and breast cancers and benign ovarian tumor was analyzed using two-dimensional electrophoresis combined with MALDI-TOF(-TOF)-mass spectrometry, finding α-1-acid glycoprotein and clusterin are expressly down-regulated in breast cancer, whereas transthyretin is decreased specifically in ovarian cancer.