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Ekaterina V. Ilgisonis
Researcher at Russian Academy
Publications - 41
Citations - 526
Ekaterina V. Ilgisonis is an academic researcher from Russian Academy. The author has contributed to research in topics: Proteome & Human proteome project. The author has an hindex of 10, co-authored 33 publications receiving 384 citations. Previous affiliations of Ekaterina V. Ilgisonis include Russian Academy of Sciences & Engelhardt Institute of Molecular Biology.
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Journal ArticleDOI
The Size of the Human Proteome: The Width and Depth.
Elena A. Ponomarenko,Ekaterina V. Poverennaya,Ekaterina V. Ilgisonis,Mikhail A. Pyatnitskiy,Arthur T. Kopylov,Victor G. Zgoda,Andrey Lisitsa,Alexander I. Archakov +7 more
TL;DR: In this article, meta-analysis of neXtProt knowledge base is proposed for theoretical prediction of the number of different proteoforms that arise from alternative splicing (AS), single amino acid polymorphisms (SAPs), and posttranslational modifications (PTMs).
Journal ArticleDOI
Chromosome 18 Transcriptome Profiling and Targeted Proteome Mapping in Depleted Plasma, Liver Tissue and HepG2 Cells
Victor G. Zgoda,Arthur T. Kopylov,O. V. Tikhonova,Alexander A. Moisa,Nadezhda V. Pyndyk,T E Farafonova,Svetlana E. Novikova,Andrey Lisitsa,Elena A. Ponomarenko,Ekaterina V. Poverennaya,Sergey P. Radko,Svetlana A. Khmeleva,L. K. Kurbatov,Aleksey D. Filimonov,Nadezhda A. Bogolyubova,Ekaterina V. Ilgisonis,A. L. Chernobrovkin,Andrew Ivanov,Alexei Medvedev,Y. V. Mezentsev,Sergei A. Moshkovskii,Stanislav N. Naryzhny,Stanislav N. Naryzhny,Elena N. Ilina,E. S. Kostrjukova,Dmitry G. Alexeev,Alexander V. Tyakht,Vadim M. Govorun,Alexander I. Archakov +28 more
TL;DR: The final goal of the Russian part of the Chromosome-centric Human Proteome Project (C-HPP) was established as the analysis of the chromosome 18 (Chr 18) protein complement in plasma, liver tissue and HepG2 cells with the sensitivity of 10(-18) M.
Journal ArticleDOI
Chromosome 18 transcriptoproteome of liver tissue and HepG2 cells and targeted proteome mapping in depleted plasma: update 2013.
Elena A. Ponomarenko,Arthur T. Kopylov,Andrey Lisitsa,Sergey P. Radko,Y.Y. Kiseleva,L. K. Kurbatov,K.G. Ptitsyn,O. V. Tikhonova,Alexander A. Moisa,Svetlana E. Novikova,Ekaterina V. Poverennaya,Ekaterina V. Ilgisonis,Alexey D. Filimonov,Nadezhda A. Bogolubova,Valentina V. Averchuk,P. A. Karalkin,I. V. Vakhrushev,Konstantin N. Yarygin,Sergei A. Moshkovskii,Victor G. Zgoda,A. S. Sokolov,Alexander M. Mazur,Egor B. Prokhortchouck,Egor B. Prokhortchouck,Konstantin G. Skryabin,Konstantin G. Skryabin,Elena N. Ilina,E. S. Kostrjukova,Dmitry G. Alexeev,Alexander V. Tyakht,Alexey Y. Gorbachev,Vadim M. Govorun,Alexander I. Archakov +32 more
TL;DR: For liver tissue and HepG2 cells a "transcriptoproteome" was produced that reflects the relationship between transcript and protein copy numbers of the genes on Chr 18, and was uploaded into the "Update_2013" data set of the knowledgebase (www.kb18.ru) and investigated for linear correlations.
Journal ArticleDOI
Exome‐based proteogenomics of HEK‐293 human cell line: Coding genomic variants identified at the level of shotgun proteome
Anna A. Lobas,Anna A. Lobas,Dmitry S. Karpov,Arthur T. Kopylov,Elizaveta M. Solovyeva,Elizaveta M. Solovyeva,Mark V. Ivanov,Mark V. Ivanov,Irina Y. Ilina,Vassily N. Lazarev,Ksenia G. Kuznetsova,Ekaterina V. Ilgisonis,Victor G. Zgoda,Mikhail V. Gorshkov,Mikhail V. Gorshkov,Sergei A. Moshkovskii +15 more
TL;DR: Genomic and proteomic data were integrated into the proteogenomic workflow to identify coding genomic variants of Human Embryonic Kidney 293 (HEK‐293) cell line at the proteome level, and eight of the proteins bearing amino acid variants were annotated as cancer‐related ones, including p53 tumor suppressor.
Journal ArticleDOI
Targeted Quantitative Screening of Chromosome 18 Encoded Proteome in Plasma Samples of Astronaut Candidates.
A. T. Kopylov,Ekaterina V. Ilgisonis,Alexander Moysa,O. V. Tikhonova,Maria G. Zavialova,Svetlana E. Novikova,Andrey Lisitsa,Elena A. Ponomarenko,Sergei A. Moshkovskii,Andrey A. Markin,Anatoly I. Grigoriev,Victor G. Zgoda,Alexander I. Archakov +12 more
TL;DR: This work was aimed at estimating the concentrations of proteins encoded by human chromosome 18 (Chr 18) in plasma samples of 54 healthy male volunteers (aged 20-47) and provides a background for studies of a potential biomarker in plasma among proteins encode by Chr 18.