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Alexander Kupferthaler
Researcher at Austrian Academy of Sciences
Publications - 18
Citations - 876
Alexander Kupferthaler is an academic researcher from Austrian Academy of Sciences. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 9 publications receiving 713 citations. Previous affiliations of Alexander Kupferthaler include Innsbruck Medical University.
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Journal ArticleDOI
Isoprene and acetone concentration profiles during exercise on an ergometer
Julian King,Alexander Kupferthaler,Alexander Kupferthaler,Karl Unterkofler,Karl Unterkofler,Helin Koc,Helin Koc,Helin Koc,Susanne Teschl,Gerald Teschl,Wolfram Miekisch,Wolfram Miekisch,Jochen K. Schubert,Jochen K. Schubert,Hartmann Hinterhuber,Hartmann Hinterhuber,Anton Amann,Anton Amann +17 more
TL;DR: Data appear to favor the hypothesis that short-term effects visible in breath isoprene levels are mainly caused by changes in pulmonary gas exchange patterns rather than fluctuations in endogenous synthesis, and hold great potential in capturing continuous dynamics of non-polar, low-soluble VOCs over a wide measurement range.
Journal ArticleDOI
Dynamic profiles of volatile organic compounds in exhaled breath as determined by a coupled PTR-MS/GC-MS study.
Julian King,Julian King,Pawel Mochalski,Alexander Kupferthaler,Alexander Kupferthaler,Karl Unterkofler,Karl Unterkofler,H. Koc,H. Koc,Wojciech Filipiak,Wojciech Filipiak,Susanne Teschl,Hartmann Hinterhuber,Hartmann Hinterhuber,Anton Amann,Anton Amann +15 more
TL;DR: These investigations aim at evaluating the impact of breathing patterns, cardiac output or blood pressure on the observed breath concentration and allow for the detection and identification of several VOCs revealing characteristic rest-to-work transitions in response to variations in ventilation or perfusion.
Journal ArticleDOI
Physiological modeling of isoprene dynamics in exhaled breath
Julian King,Helin Koc,Helin Koc,Karl Unterkofler,Karl Unterkofler,PaweŁ Mochalski,Alexander Kupferthaler,Gerald Teschl,Susanne Teschl,Hartmann Hinterhuber,Anton Amann,Anton Amann +11 more
TL;DR: A thorough modeling study of the end-tidal breath dynamics associated with isoprene, which serves as a paradigmatic example for the class of low-soluble, blood-borne VOCs, is devoted to aid further investigations regarding the exhalation, storage, transport and biotransformation processes associated with this important compound.
Journal ArticleDOI
Measurement of endogenous acetone and isoprene in exhaled breath during sleep
Julian King,Alexander Kupferthaler,Alexander Kupferthaler,Birgit Frauscher,Heinz Hackner,Karl Unterkofler,Karl Unterkofler,Gerald Teschl,Hartmann Hinterhuber,Anton Amann,Anton Amann,Birgit Högl +11 more
TL;DR: Breath acetone andIsoprene profiles exhibited pronounced concentration peaks, which were highly specific for leg movements as scored by tibial electromyography, and baseline isoprene concentrations decreased during the transition from the NREM to the REM phase of a complete sleep cycle.
Journal ArticleDOI
Isoprene and acetone concentration profiles during exercise on an ergometer
Julian King,Alexander Kupferthaler,Alexander Kupferthaler,Karl Unterkofler,Karl Unterkofler,Helin Koc,Helin Koc,Helin Koc,Susanne Teschl,Gerald Teschl,Wolfram Miekisch,Wolfram Miekisch,Jochen K. Schubert,Jochen K. Schubert,Hartmann Hinterhuber,Hartmann Hinterhuber,Anton Amann,Anton Amann +17 more
TL;DR: A real-time recording setup combining exhaled breath VOC measurements by proton transfer reaction mass spectrometry (PTR-MS) with hemodynamic and respiratory data is presented in this paper.