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Anette Veringa
Researcher at University Medical Center Groningen
Publications - 19
Citations - 461
Anette Veringa is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Voriconazole & Therapeutic drug monitoring. The author has an hindex of 8, co-authored 15 publications receiving 328 citations.
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Journal ArticleDOI
Therapeutic Drug Monitoring of Posaconazole: an Update
Bart G. J. Dekkers,Martijn Bakker,Kim C. M. van der Elst,Marieke G G Sturkenboom,Anette Veringa,Lambert F.R. Span,Jan-Willem C. Alffenaar +6 more
TL;DR: The most recent findings on pharmacokinetics and pharmacodynamics of posaconazole in the setting of prophylaxis and treatment of fungal infections are highlighted and the challenges associated with TDM are referred to.
Journal ArticleDOI
Voriconazole metabolism is influenced by severe inflammation : a prospective study
Anette Veringa,Mendy ter Avest,Lambert F.R. Span,Edwin R. van den Heuvel,Daan J Touw,Jan G. Zijlstra,Jos G. W. Kosterink,Jos G. W. Kosterink,Tjip S. van der Werf,Jan-Willem C. Alffenaar +9 more
TL;DR: It is shown that voriconazole metabolism is decreased during inflammation, resulting in higher vor Iconazole trough concentrations, and frequent monitoring of vorIconazole serum concentrations is recommended during and following severe inflammation.
Journal ArticleDOI
LC-MS/MS for Therapeutic Drug Monitoring of anti-infective drugs
Anette Veringa,Marieke G G Sturkenboom,Bart G. J. Dekkers,Remco A. Koster,Jason A. Roberts,Charles A. Peloquin,Charles A. Peloquin,Daan J Touw,Jan-Willem C. Alffenaar +8 more
TL;DR: The current challenges in the bioanalysis of anti-infective drugs are reviewed and insight is given in the pre- and postanalytical issues surrounding TDM.
Journal ArticleDOI
Low Caspofungin Exposure in Patients in Intensive Care Units
Kim C. M. van der Elst,Anette Veringa,Jan G. Zijlstra,Albertus Beishuizen,Rob Klont,Petra Brummelhuis-Visser,Donald R. A. Uges,Daan J Touw,Jos G. W. Kosterink,Jos G. W. Kosterink,Tjip S. van der Werf,Jan-Willem C. Alffenaar +11 more
TL;DR: The caspofungin exposure in ICU patients in this study was low compared with that in healthy volunteers and other (non)critically ill patients, most likely due to a larger volume of distribution.
Journal ArticleDOI
Pharmacodynamics of Voriconazole in Children: Further Steps along the Path to True Individualized Therapy
Luc J. Huurneman,Michael Neely,Anette Veringa,Fernando Docobo Pérez,Virginia Ramos-Martin,Wim J. E. Tissing,Jan-Willem C. Alffenaar,William W. Hope +7 more
TL;DR: The construction of linked PK-PD models is the first step in developing control software that enables not only individualized voriconazole dosages but also individualized concentration targets to achieve suppression of galactomannan levels in a timely and optimally precise manner.