Botao Zhang

TL;DR: In this paper, the CRISPR/Cas9-induced gene mutations in Arabidopsis were mostly somatic mutations in the early generation, although some mutations could be stably inherited in later generations.

TL;DR: The work demonstrates that the CRISPR/Cas method can effectively create specific gene modifications in planta that are stably transmitted through the germ line to future generations and is a useful tool for generating versatile and heritable modifications specifically at target genes in plants.

TL;DR: It is shown that the CRISPR–Cas system can be applied to generate targeted gene mutations and gene corrections in plants, and the system can also be readily engineered to achieve deletion of large DNA fragments and for multiplex gene editing in plants.

TL;DR: These genes provide new model systems to study mitochondrial retrograde regulation, in addition to the widely used alternative oxidase model, as changes in proteins responsive to stress did not correlate well with changes at a transcript level, it suggests that post-transcriptional mechanisms also play an important role in defining the MSR.