L
Lan Yang
Researcher at Chinese Academy of Sciences
Publications - 20
Citations - 2322
Lan Yang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: DNA methylation & RNA-Directed DNA Methylation. The author has an hindex of 15, co-authored 19 publications receiving 1794 citations. Previous affiliations of Lan Yang include Laboratory of Molecular Biology.
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Journal ArticleDOI
The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation
Hui Zhang,Jinshan Zhang,Pengliang Wei,Botao Zhang,Feng Gou,Zhengyan Feng,Yanfei Mao,Lan Yang,Heng Zhang,Nanfei Xu,Jian-Kang Zhu,Jian-Kang Zhu +11 more
TL;DR: In this paper, the CRISPR/Cas9-induced gene mutations in Arabidopsis were mostly somatic mutations in the early generation, although some mutations could be stably inherited in later generations.
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Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis
Zhengyan Feng,Yanfei Mao,Nanfei Xu,Botao Zhang,Pengliang Wei,Dong-Lei Yang,Zhen Wang,Zhengjing Zhang,Rui Zheng,Lan Yang,Liang Zeng,Xiaodong Liu,Jian-Kang Zhu,Jian-Kang Zhu +13 more
TL;DR: The work demonstrates that the CRISPR/Cas method can effectively create specific gene modifications in planta that are stably transmitted through the germ line to future generations and is a useful tool for generating versatile and heritable modifications specifically at target genes in plants.
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Transposable elements (TEs) contribute to stress-related long intergenic noncoding RNAs in plants.
Dong Wang,Zhipeng Qu,Lan Yang,Qingzhu Zhang,Zhi‐Hong Liu,Trung Do,David L. Adelson,Zhen-Yu Wang,Iain R. Searle,Jian-Kang Zhu,Jian-Kang Zhu +10 more
TL;DR: These findings not only demonstrate that TE-associated lincRNAs play important roles in plant abiotic stress responses but linc RNAs and TE-lincRNas might act as an adaptive reservoir in eukaryotes.
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Dicer-independent RNA-directed DNA methylation in Arabidopsis
Dong-Lei Yang,Guiping Zhang,Kai Tang,Jingwen Li,Lan Yang,Huan Huang,Heng Zhang,Jian-Kang Zhu,Jian-Kang Zhu +8 more
TL;DR: The results suggest that RdDM in plants is largely guided by a previously unappreciated class of Dicer-independent non-coding RNAs, and that siRNAs are required to maintain DNA methylation at only a subset of loci.
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Generation of a multiplex mutagenesis population via pooled CRISPR-Cas9 in soya bean.
Mengyan Bai,Juehui Yuan,Huaqin Kuang,Pingping Gong,Suning Li,Zhihui Zhang,Bo Liu,Jiafeng Sun,Maoxiang Yang,Lan Yang,Dong Wang,Shikui Song,Yuefeng Guan +12 more
TL;DR: This study provides an advanced strategy for the generation of a targeted multiplex mutant population to overcome the gene redundancy problem in soya bean as well as in other major crops.