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David L. Buckley

Researcher at University of Leeds

Publications -  136
Citations -  11559

David L. Buckley is an academic researcher from University of Leeds. The author has contributed to research in topics: Dynamic contrast-enhanced MRI & Magnetic resonance imaging. The author has an hindex of 51, co-authored 126 publications receiving 10632 citations. Previous affiliations of David L. Buckley include Hull Royal Infirmary & Manchester Academic Health Science Centre.

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Imaging biomarker roadmap for cancer studies.

James P B O'Connor, +78 more
TL;DR: Experts assembled to review, debate and summarize the challenges of IB validation and qualification produced 14 key recommendations for accelerating the clinical translation of IBs, which highlight the role of parallel (rather than sequential) tracks of technical validation, biological/clinical validation and assessment of cost-effectiveness.
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Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI.

TL;DR: Rapid T1‐weighted 3D spoiled gradient‐echo data sets were acquired in the abdomen of 23 cancer patients during a total of 113 separate visits to allow dynamic contrast‐enhanced MRI (DCE‐MRI) analysis of tumor microvasculature to indicate the potential for increased sensitivity to therapy‐induced change.
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Tracer kinetic modelling in MRI: estimating perfusion and capillary permeability

TL;DR: An overview of tracer-kinetic models developed in the early 1990s for dynamic contrast-enhanced MRI (DCE-MRI) is provided, offering researchers a clearer understanding of their assumptions and requirements.
Journal ArticleDOI

Classic models for dynamic contrast-enhanced MRI.

TL;DR: Dynamic contrast‐enhanced MRI (DCE‐MRI) is a functional MRI method where T1 ‐weighted MR images are acquired dynamically after bolus injection of a contrast agent.