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Robert M. Weisskoff
Researcher at Harvard University
Publications - 129
Citations - 35121
Robert M. Weisskoff is an academic researcher from Harvard University. The author has contributed to research in topics: Magnetic resonance imaging & Cerebral blood flow. The author has an hindex of 75, co-authored 129 publications receiving 33955 citations. Previous affiliations of Robert M. Weisskoff include Massachusetts Institute of Technology & Beth Israel Deaconess Medical Center.
Papers
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Journal ArticleDOI
Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation.
Kenneth K. Kwong,John W. Belliveau,David A. Chesler,Inna E. Goldberg,Robert M. Weisskoff,Brigitte P. Poncelet,David N. Kennedy,Bernice E. Hoppel,Mark S. Cohen,Robert Turner,Hong-Ming Cheng,Thomas J. Brady,Bruce R. Rosen +12 more
TL;DR: In this paper, a series of images were acquired continuously with the same imaging pulse sequence (either gradient echo or spin-echo inversion recovery) during task activation, and a significant increase in signal intensity (paired t test; P less than 0.001) of 1.8% +/- 0.9% was observed in the primary visual cortex (V1) of seven normal volunteers.
Journal ArticleDOI
Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols.
Paul S. Tofts,Gunnar Brix,David L. Buckley,Jeffrey L. Evelhoch,Elizabeth Henderson,Michael V. Knopp,Henrik Larsson,Ting-Yim Lee,Nina A. Mayr,Geoffrey J. M. Parker,Ruediger E. Port,June S. Taylor,Robert M. Weisskoff +12 more
TL;DR: A standard set of quantity names and symbols related to the estimation of kinetic parameters from dynamic contrast‐enhanced T1‐weighted magnetic resonance imaging data, using diffusable agents such as gadopentetate dimeglumine (Gd‐DTPA), are described.
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Functional mapping of the human visual cortex by magnetic resonance imaging
John W. Belliveau,David N. Kennedy,Robert C. McKinstry,Bradley R. Buchbinder,Robert M. Weisskoff,Mark S. Cohen,James M. Vevea,Thomas J. Brady,Bruce R. Rosen +8 more
TL;DR: This technique was used to generate the first functional magnetic resonance maps of human task activation, by using a visual stimulus paradigm, and localized increases in blood volume were detected in the primary visual cortex during photic stimulation.
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High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysis
TL;DR: Comparisons showed that a nonparametric deconvolution technique (singular value decomposition) allows estimation of flow relatively independent of underlying vascular structure and volume even at low signal‐to‐noise ratio associated with pixel‐by‐pixel deconvolved.
Journal ArticleDOI
Mapping complex tissue architecture with diffusion spectrum magnetic resonance imaging.
Van J. Wedeen,Patric Hagmann,Patric Hagmann,Wen-Yih Isaac Tseng,Timothy G. Reese,Robert M. Weisskoff +5 more
TL;DR: Methods are presented to map complex fiber architectures in tissues by imaging the 3D spectra of tissue water diffusion with MR, showing correspondence between the orientational maxima of the diffusion spectrum and those of the fiber orientation density at each location.