D
Dmitry Penzar
Researcher at Moscow State University
Publications - 17
Citations - 6810
Dmitry Penzar is an academic researcher from Moscow State University. The author has contributed to research in topics: DNA binding site & Transcription factor. The author has an hindex of 7, co-authored 13 publications receiving 4683 citations. Previous affiliations of Dmitry Penzar include Moscow Institute of Physics and Technology & Russian Academy of Sciences.
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Journal ArticleDOI
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Alexander E. Gorbalenya,Susan C. Baker,Ralph S. Baric,Raoul J. de Groot,Christian Drosten,Anastasia A. Gulyaeva,Bart L. Haagmans,Chris Lauber,Andrey M. Leontovich,Benjamin W. Neuman,Dmitry Penzar,Stanley Perlman,Leo L.M. Poon,Dmitry V. Samborskiy,Igor A. Sidorov,Isabel Sola,John Ziebuhr +16 more
TL;DR: The independent zoonotic transmission of SARS-CoV and SARS -CoV-2 highlights the need for studying viruses at the species level to complement research focused on individual pathogenic viruses of immediate significance.
Posted ContentDOI
Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group
Alexander E. Gorbalenya,Alexander E. Gorbalenya,Susan C. Baker,Ralph S. Baric,Raoul J. de Groot,Christian Drosten,Anastasia A. Gulyaeva,Bart L. Haagmans,Chris Lauber,Andrey M. Leontovich,Benjamin W. Neuman,Dmitry Penzar,Stanley Perlman,Leo L.M. Poon,Dmitry V. Samborskiy,Igor A. Sidorov,Isabel Solá Gurpegui,John Ziebuhr +17 more
TL;DR: The Coronavirus Study Group (CSG) of the International Committee on Taxonomy of Viruses assessed the novelty of the human pathogen tentatively named 2019-nCoV and formally recognizes this virus as a sister to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
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H3K4me3, H3K9ac, H3K27ac, H3K27me3 and H3K9me3 Histone Tags Suggest Distinct Regulatory Evolution of Open and Condensed Chromatin Landmarks.
Anna A. Igolkina,Arsenii O. Zinkevich,Kristina O. Karandasheva,Aleksey Popov,Maria V. Selifanova,Daria D. Nikolaeva,Victor Tkachev,Dmitry Penzar,Dmitry Penzar,Daniil Nikitin,Anton Buzdin +10 more
TL;DR: In humans, transposon-linked histone marks evolved in a coordinated way depending on their functional roles according to their regulatory evolution rates, and showed different regulatory patterns and formed two distinct clusters.
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Integration of multiple epigenomic marks improves prediction of variant impact in saturation mutagenesis reporter assay.
Dustin Shigaki,Orit Adato,Aashish N. Adhikari,Shengcheng Dong,Alex Hawkins-Hooker,Fumitaka Inoue,Tamar Juven-Gershon,Henry Kenlay,Beth Martin,Ayoti Patra,Dmitry Penzar,Dmitry Penzar,Max Schubach,Chenling Xiong,Zhongxia Yan,Alan P. Boyle,Anat Kreimer,Anat Kreimer,Ivan V. Kulakovskiy,Ivan V. Kulakovskiy,Ivan V. Kulakovskiy,John E. Reid,John E. Reid,Ron Unger,Nir Yosef,Jay Shendure,Nadav Ahituv,Martin Kircher,Martin Kircher,Michael A. Beer +29 more
TL;DR: Results from the CAGI 5 regulation saturation challenge are reported, which identify the most successful models of transcription factor binding sites, machine learning algorithms, and ways to choose among or incorporate diverse datatypes and cell‐types for training computational models.
Journal ArticleDOI
Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study
Giovanna Ambrosini,Giovanna Ambrosini,Ilya E. Vorontsov,Dmitry Penzar,Dmitry Penzar,Dmitry Penzar,Romain Groux,Romain Groux,Oriol Fornes,Daria D. Nikolaeva,Benoit Ballester,Jan Grau,Ivo Grosse,Vsevolod J. Makeev,Vsevolod J. Makeev,Vsevolod J. Makeev,Ivan V. Kulakovskiy,Ivan V. Kulakovskiy,Philipp Bucher,Philipp Bucher +19 more
TL;DR: Results from all-against-all benchmarking of PWM models for DNA binding sites of human TFs on a large compilation of in vitro (HT-SELEX, PBM) and in vivo (ChIP-seq) binding data are reported.