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Benjamin W. Neuman
Researcher at Texas A&M University–Texarkana
Publications - 74
Citations - 11232
Benjamin W. Neuman is an academic researcher from Texas A&M University–Texarkana. The author has contributed to research in topics: Coronavirus & RNA. The author has an hindex of 30, co-authored 67 publications receiving 8325 citations. Previous affiliations of Benjamin W. Neuman include Texas A&M University & University of Reading.
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Journal ArticleDOI
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Alexander E. Gorbalenya,Susan C. Baker,Ralph S. Baric,Raoul J. de Groot,Christian Drosten,Anastasia A. Gulyaeva,Bart L. Haagmans,Chris Lauber,Andrey M. Leontovich,Benjamin W. Neuman,Dmitry Penzar,Stanley Perlman,Leo L.M. Poon,Dmitry V. Samborskiy,Igor A. Sidorov,Isabel Sola,John Ziebuhr +16 more
TL;DR: The independent zoonotic transmission of SARS-CoV and SARS -CoV-2 highlights the need for studying viruses at the species level to complement research focused on individual pathogenic viruses of immediate significance.
Posted ContentDOI
Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group
Alexander E. Gorbalenya,Alexander E. Gorbalenya,Susan C. Baker,Ralph S. Baric,Raoul J. de Groot,Christian Drosten,Anastasia A. Gulyaeva,Bart L. Haagmans,Chris Lauber,Andrey M. Leontovich,Benjamin W. Neuman,Dmitry Penzar,Stanley Perlman,Leo L.M. Poon,Dmitry V. Samborskiy,Igor A. Sidorov,Isabel Solá Gurpegui,John Ziebuhr +17 more
TL;DR: The Coronavirus Study Group (CSG) of the International Committee on Taxonomy of Viruses assessed the novelty of the human pathogen tentatively named 2019-nCoV and formally recognizes this virus as a sister to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
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Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
Roland Züst,Roland Züst,Luisa Cervantes-Barragan,Matthias Habjan,Reinhard Maier,Benjamin W. Neuman,John Ziebuhr,John Ziebuhr,Kristy J. Szretter,Susan C. Baker,Winfried Barchet,Michael S. Diamond,Stuart G. Siddell,Burkhard Ludewig,Burkhard Ludewig,Volker Thiel,Volker Thiel +16 more
TL;DR: It is demonstrated that the induction of type I interferon by viruses deficient in 2′-O-methyltransferase was dependent on the cytoplasmic RNA sensor Mda5, which suggests that RNA modifications such as 2-methylation provide a molecular signature for the discrimination of self and non-self mRNA.
Journal ArticleDOI
A structural analysis of M protein in coronavirus assembly and morphology
Benjamin W. Neuman,Gabriella Kiss,Andreas Hjarne Kunding,David Bhella,M. Fazil Baksh,Stephen Connelly,Ben Droese,Joseph P. Klaus,Shinji Makino,Stanley G. Sawicki,Stuart G. Siddell,Dimitrios Stamou,Ian A. Wilson,Peter Kuhn,Michael J. Buchmeier +14 more
TL;DR: Evidence is presented that suggests M can adopt two conformations and that membrane curvature is regulated by one M conformer, providing insight into how M protein functions to promote virus assembly.
Journal ArticleDOI
Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles
TL;DR: Transfection of plasmid constructs encoding full-length versions of the three transmembrane-containing nonstructural proteins of the severe acute respiratory syndrome (SARS) coronavirus are used to examine the ability of each to induce double- Membrane vesicles in tissue culture.