J
John Ziebuhr
Researcher at University of Giessen
Publications - 140
Citations - 24202
John Ziebuhr is an academic researcher from University of Giessen. The author has contributed to research in topics: Coronavirus & RNA. The author has an hindex of 54, co-authored 132 publications receiving 18492 citations. Previous affiliations of John Ziebuhr include Queen's University Belfast & University of Jena.
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Journal ArticleDOI
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Alexander E. Gorbalenya,Susan C. Baker,Ralph S. Baric,Raoul J. de Groot,Christian Drosten,Anastasia A. Gulyaeva,Bart L. Haagmans,Chris Lauber,Andrey M. Leontovich,Benjamin W. Neuman,Dmitry Penzar,Stanley Perlman,Leo L.M. Poon,Dmitry V. Samborskiy,Igor A. Sidorov,Isabel Sola,John Ziebuhr +16 more
TL;DR: The independent zoonotic transmission of SARS-CoV and SARS -CoV-2 highlights the need for studying viruses at the species level to complement research focused on individual pathogenic viruses of immediate significance.
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Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of Anti-SARS Drugs
TL;DR: Molecular modeling suggests that available rhinovirus 3Cpro inhibitors may be modified to make them useful for treating SARS, and a homology model for SARS coronavirus (SARS-CoV) Mpro is constructed.
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Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage.
Eric J. Snijder,Peter J. Bredenbeek,Jessika C. Dobbe,Volker Thiel,John Ziebuhr,Leo L.M. Poon,Yi Guan,Mikhail Rozanov,Willy J. M. Spaan,Alexander E. Gorbalenya +9 more
TL;DR: These newly recognized viral enzymes place the mechanism of coronavirus RNA synthesis in a completely new perspective and will be important targets for the design of antiviral strategies aimed at controlling the further spread of SARS-CoV.
Posted ContentDOI
Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group
Alexander E. Gorbalenya,Alexander E. Gorbalenya,Susan C. Baker,Ralph S. Baric,Raoul J. de Groot,Christian Drosten,Anastasia A. Gulyaeva,Bart L. Haagmans,Chris Lauber,Andrey M. Leontovich,Benjamin W. Neuman,Dmitry Penzar,Stanley Perlman,Leo L.M. Poon,Dmitry V. Samborskiy,Igor A. Sidorov,Isabel Solá Gurpegui,John Ziebuhr +17 more
TL;DR: The Coronavirus Study Group (CSG) of the International Committee on Taxonomy of Viruses assessed the novelty of the human pathogen tentatively named 2019-nCoV and formally recognizes this virus as a sister to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
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Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group.
Raoul J. de Groot,Susan C. Baker,Ralph S. Baric,Caroline Brown,Christian Drosten,Luis Enjuanes,Ron A. M. Fouchier,Monica Galiano,Alexander E. Gorbalenya,Ziad A. Memish,Stanley Perlman,Leo L.M. Poon,Eric J. Snijder,Gwen Stephens,Patrick C. Y. Woo,Ali Moh Zaki,Maria Zambon,John Ziebuhr +17 more
TL;DR: During the summer of 2012, in Jeddah, Saudi Arabia, a hitherto unknown coronavirus was isolated from the sputum of a patient with acute pneumonia and renal failure and was provisionally called human coronav virus Erasmus Medical Center (EMC).