E
Elizabeth McKinnon
Researcher at Murdoch University
Publications - 90
Citations - 3849
Elizabeth McKinnon is an academic researcher from Murdoch University. The author has contributed to research in topics: Human leukocyte antigen & Stavudine. The author has an hindex of 26, co-authored 90 publications receiving 3702 citations. Previous affiliations of Elizabeth McKinnon include University of Western Australia & Royal Perth Hospital.
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Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection.
TL;DR: NRTIs do have an independent contribution to fat wasting, but PI are the predominant influence and may act synergistically with NRTIs, suggesting a non-linear decline in fat over time.
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Immune restoration disease after the treatment of immunodeficient HIV‐infected patients with highly active antiretroviral therapy
Martyn A. French,Nat Lenzo,Mina John,Simon Mallal,Elizabeth McKinnon,Ian James,Patricia Price,James Flexman,M-L. Tay-Kearney +8 more
TL;DR: A single‐centre retrospective study of all HIV‐infected patients commencing HAART prior to 1 July 1997 was undertaken to determine the incidence, characteristics and time of onset of disease episodes in HAART responders.
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Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy
TL;DR: Treatment with stavudine appears to be the predominant risk factor for development of chronic hyperlactatemia in HIV-infected patients, and was not significantly associated with use of other NRTIs, protease inhibitors, non-nucleoside analogue reverse transcriptase inhibitors or multiple immunological and virological factors in multivariate analyses.
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Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy.
David Nolan,Emma Hammond,Annalise M Martin,Louise Taylor,Susan Herrmann,Elizabeth McKinnon,Cecily Metcalf,Bruce Latham,Simon Mallal +8 more
TL;DR: NRTI therapy is associated with mtDNA depletion and mitochondrial proliferation in adipocytes, consistent with the hypothesis that NRTI‐induced mt DNA depletion contributes to the pathogenesis of subcutaneous fat wasting.
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Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study
Andri Rauch,David Nolan,Annalise M Martin,Elizabeth McKinnon,Coral-Ann M. Almeida,Simon Mallal +5 more
TL;DR: The usefulness of genetic risk stratification is confirmed, with no cases of abacavir hypersensitivity among 148 HLA-B*5701-negative recipients.