Georg Andreas Gundersen

TL;DR: An anatomically distinct clearing system in the brain that serves a lymphatic-like function is described and may have relevance for understanding or treating neurodegenerative diseases that involve the mis-accumulation of soluble proteins, such as amyloid β in Alzheimer's disease.

TL;DR: The data suggest that the blood–brain barrier (BBB) is more complex than anticipated, and under certain conditions, the astrocyte covering of brain microvessels is rate limiting to water movement.

TL;DR: Combined K+ and extracellular volume recordings indicate that compromised K+ spatial buffering in brain underlies the epilepsy phenotype associated with human KCNJ10 mutations.

TL;DR: The data support the concept that pericytes regulate AQP4 polarization, a member of the dystrophin-associated protein complex (DAPC), and the enrichment of α-syntrophin in membranes ensheathingpericytes persisted after Aqp4 gene deletion.

TL;DR: It is concluded that Aqp4 deletion reduces the expression of perivascular glial scaffolding proteins without affecting the endothelial barrier and that AQP4 and α‐syntrophin are mutually dependent upon each other for proper periv vascular expression.