S
Steven A. Goldman
Researcher at University of Rochester Medical Center
Publications - 321
Citations - 35976
Steven A. Goldman is an academic researcher from University of Rochester Medical Center. The author has contributed to research in topics: Progenitor cell & Neural stem cell. The author has an hindex of 85, co-authored 301 publications receiving 31653 citations. Previous affiliations of Steven A. Goldman include NewYork–Presbyterian Hospital & University of Pennsylvania.
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Journal ArticleDOI
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.
Jeffrey J. Iliff,Minghuan Wang,Minghuan Wang,Yonghong Liao,Benjamin A. Plogg,Weiguo Peng,Georg Andreas Gundersen,Helene Benveniste,G. Edward Vates,Rashid Deane,Steven A. Goldman,Erlend A. Nagelhus +11 more
TL;DR: An anatomically distinct clearing system in the brain that serves a lymphatic-like function is described and may have relevance for understanding or treating neurodegenerative diseases that involve the mis-accumulation of soluble proteins, such as amyloid β in Alzheimer's disease.
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New roles for astrocytes: redefining the functional architecture of the brain
TL;DR: The net effect is that astroglia demarcate gray matter regions, both cortical and subcortical, into functional compartments whose internal activation thresholds and external outputs are regulated by single glial cells.
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Uniquely hominid features of adult human astrocytes
Nancy Ann Oberheim,Takahiro Takano,Xiaoning Han,Wei He,Jane H.-C. Lin,Fushun Wang,Qiwu Xu,Jeffrey D. Wyatt,Webster H. Pilcher,Jeffrey G. Ojemann,Bruce R. Ransom,Steven A. Goldman +11 more
TL;DR: It is reported here that protoplasmic astrocytes in human neocortex are 2.6-fold larger in diameter and extend 10-fold more GFAP (glial fibrillary acidic protein)-positive primary processes than their rodent counterparts, and it is posited that thisAstrocytic complexity has permitted the increased functional competence of the adult human brain.
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Effect of Vasodilator Therapy on Mortality in Chronic Congestive Heart Failure. Results of a Veterans Administration Cooperative Study
Jay N. Cohn,Donald G. Archibald,Susan Ziesche,Joseph A. Franciosa,W. E. Harston,Felix E. Tristani,W. B. Dunkman,William R. Jacobs,Gary S. Francis,K. H. Flohr,Steven A. Goldman,Frederick R. Cobb,Prediman K. Shah,Robert S. Saunders,Robert H. Fletcher,Henry S. Loeb,V. Hughes,Bonnie J. Baker +17 more
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Neuronal production, migration, and differentiation in a vocal control nucleus of the adult female canary brain
TL;DR: It is concluded that neuronal precursors exist in the HVc ventricular zone that incorporate tritiated thymidine during the S phase preceding their mitosis; after division these cells migrate into, and to some extent beyond, HVm, which seems to be a normally occurring phenomenon in intact adult female canaries.