H
Harihara M. Mehendale
Researcher at University of Louisiana at Monroe
Publications - 134
Citations - 5405
Harihara M. Mehendale is an academic researcher from University of Louisiana at Monroe. The author has contributed to research in topics: Liver injury & Thioacetamide. The author has an hindex of 40, co-authored 134 publications receiving 5152 citations.
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Journal ArticleDOI
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework
Edward J. Calabrese,Kenneth Bachmann,A. John Bailer,P. Michael Bolger,Jonathan Borak,Lu Cai,Nina Cedergreen,M. George Cherian,Chuang Chin Chiueh,Thomas W. Clarkson,Ralph R. Cook,David M. Diamond,David J. Doolittle,Michael A. Dorato,Stephen O. Duke,Ludwig E. Feinendegen,Donald E. Gardner,Ronald W. Hart,Kenneth L. Hastings,A. Wallace Hayes,George R. Hoffmann,John A. Ives,Zbigniew Jaworowski,Thomas E. Johnson,Wayne B. Jonas,Norbert E. Kaminski,John G. Keller,James E. Klaunig,Thomas B. Knudsen,Walter J. Kozumbo,Teresa Lettieri,Shu Zheng Liu,Andre Maisseu,Kenneth I. Maynard,Edward J. Masoro,Roger O. McClellan,Harihara M. Mehendale,Carmel Mothersill,David B. Newlin,Herbert N. Nigg,Frederick W. Oehme,Robert F. Phalen,Martin A. Philbert,Suresh I. S. Rattan,Jim E. Riviere,Joseph Rodricks,Robert M. Sapolsky,Bobby R. Scott,Colin Seymour,David A. Sinclair,Joan Smith-Sonneborn,Elizabeth T. Snow,Linda P. Spear,Donald E. Stevenson,Yolene Thomas,Maurice Tubiana,Gary M. Williams,Mark P. Mattson +57 more
TL;DR: This article offers a set of recommendations that scientists believe can achieve greater conceptual harmony in dose-response terminology, as well as better understanding and communication across the broad spectrum of biological disciplines.
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Tissue repair: an important determinant of final outcome of toxicant-induced injury.
TL;DR: The significance of tissue repair as a target for drug development strategies and an important consideration in the assessment of risk from exposure to toxicants is highlighted.
Journal Article
Cationic amphiphilic drugs and phospholipid storage disorder.
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Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and β-catenin signaling
Yong-Yu Liu,Vineet Gupta,Gauri A. Patwardhan,Kaustubh N. Bhinge,Yunfeng Zhao,Jianxiong Bao,Harihara M. Mehendale,Myles C. Cabot,Yu-Teh Li,S. Michal Jazwinski +9 more
TL;DR: This study demonstrates, for the first time, that GCS upregulates MDR1 expression modulating drug resistance of cancer.
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Saturation toxicokinetics of thioacetamide: role in initiation of liver injury.
TL;DR: With increasing doses, the apparent elimination half-lives of TA and TASO increased linearly, indicating that TA bioactivation exhibits saturation kinetics, and indicates saturation of CYP2E1 at the first and second steps of TA bio activation.