D
David A. Sinclair
Researcher at Harvard University
Publications - 506
Citations - 81398
David A. Sinclair is an academic researcher from Harvard University. The author has contributed to research in topics: Sirtuin & NAD+ kinase. The author has an hindex of 106, co-authored 477 publications receiving 70934 citations. Previous affiliations of David A. Sinclair include TRIUMF & University of British Columbia.
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Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky,Fábio Camargo Abdalla,Hagai Abeliovich,Robert T. Abraham,Abraham Acevedo-Arozena,Khosrow Adeli,Lotta Agholme,Maria Agnello,Patrizia Agostinis,Julio A. Aguirre-Ghiso,Hyung Jun Ahn,Ouardia Ait-Mohamed,Slimane Ait-Si-Ali,Takahiko Akematsu,Shizuo Akira,Hesham M. Al-Younes,Munir A. Al-Zeer,Matthew L. Albert,Roger L. Albin,Javier Alegre-Abarrategui,Maria Francesca Aleo,Mehrdad Alirezaei,Alexandru Almasan,Maylin Almonte-Becerril,Atsuo Amano,Ravi K. Amaravadi,Shoba Amarnath,Amal O. Amer,Nathalie Andrieu-Abadie,Vellareddy Anantharam,David K. Ann,Shailendra Anoopkumar-Dukie,Hiroshi Aoki,Nadezda Apostolova,Giuseppe Arancia,John P. Aris,Katsuhiko Asanuma,Nana Asare,Hisashi Ashida,Valerie Askanas,David S. Askew,Patrick Auberger,Misuzu Baba,Steven K. Backues,Eric H. Baehrecke,Ben A. Bahr,Xue Yuan Bai,Yannick Bailly,Robert A. Baiocchi,Giulia Baldini,Walter Balduini,Andrea Ballabio,Andrea Ballabio,Bruce A. Bamber,Edward T. W. Bampton,Gábor Bánhegyi,Clinton R. Bartholomew,Diane C. Bassham,Robert C. Bast,Henri Batoko,Boon-Huat Bay,Isabelle Beau,Daniel Béchet,Thomas J. Begley,Christian Behl,Christian Behrends,Soumeya Bekri,Bryan H. Bellaire,Linda J. Bendall,Luca Benetti,Laura Berliocchi,Henri Bernardi,Francesca Bernassola,Sébastien Besteiro,Ingrid Bhatia-Kiššová,Xiaoning Bi,Martine Biard-Piechaczyk,Janice S. Blum,Lawrence H. Boise,Paolo Bonaldo,David L. Boone,Beat Bornhauser,Karina R. Bortoluci,Ioannis Bossis,Frédéric Bost,Jean-Pierre Bourquin,Patricia Boya,Michaël Boyer-Guittaut,Peter V. Bozhkov,Nathan R. Brady,Claudio Brancolini,Andreas Brech,Jay E. Brenman,Ana Brennand,Emery H. Bresnick,Patrick Brest,Dave Bridges,Molly L. Bristol,Paul S. Brookes,Eric J. Brown,John H. Brumell,Nicola Brunetti-Pierri,Ulf T. Brunk,Dennis E. Bulman,Scott J. Bultman,Geert Bultynck,Lena F. Burbulla,Wilfried Bursch,Jonathan P. Butchar,Wanda Christa Buzgariu,Sérgio Paulo Bydlowski,Ken Cadwell,Monika Cahova,Dongsheng Cai,Jiyang Cai,Qian Cai,Bruno Calabretta,Javier Calvo-Garrido,Nadine Camougrand,Michelangelo Campanella,Jenny Campos-Salinas,Eleonora Candi,Lizhi Cao,Allan Caplan,Simon R. Carding,Sandra M. Cardoso,Jennifer S. Carew,Cathleen R. Carlin,Virginie Carmignac,Leticia A.M. Carneiro,Serena Carra,Serena Carra,Rosario Caruso,Giorgio Casari,Caty Casas,Roberta Castino,Eduardo Cebollero,Francesco Cecconi,Jean Celli,Hassan Chaachouay,Han-Jung Chae,Chee Yin Chai,David C. Chan,Edmond Chan,Raymond Chuen-Chung Chang,Chi-Ming Che,Ching-Chow Chen,Guang-Chao Chen,Guo-Qiang Chen,Min Chen,Quan Chen,Quan Chen,Steve S.-L. Chen,Wen-Li Chen,Xi Chen,Xiangmei Chen,Xiequn Chen,Ye-Guang Chen,Yingyu Chen,Yongqiang Chen,Yu Jen Chen,Zhixiang Chen,Alan Cheng,Christopher H.K. Cheng,Yan Cheng,Heesun Cheong,Jae Ho Cheong,Sara Cherry,Russ Chess-Williams,Zelda H. Cheung,Eric Chevet,Hui Ling Chiang,Roberto Chiarelli,Tomoki Chiba,Lih-Shen Chin,Shih Hwa Chiou,Francis V. Chisari,Chi Hin Cho,Dong-Hyung Cho,Augustine M.K. Choi,Doo Seok Choi,Kyeong Sook Choi,Mary E. Choi,Salem Chouaib,Divaker Choubey,Vinay Choubey,Charleen T. Chu,Tsung Hsien Chuang,Sheau Huei Chueh,Taehoon Chun,Yong Joon Chwae,Mee-Len Chye,Roberto Ciarcia,Maria Rosa Ciriolo,Michael J. Clague,Robert S. B. Clark,Peter G.H. Clarke,Robert Clarke,Patrice Codogno,Hilary A. Coller,María Isabel Colombo,Sergio Comincini,Maria Condello,Fabrizio Condorelli,Mark R. Cookson,Graham H. Coombs,Isabelle Coppens,Ramón Corbalán,Pascale Cossart,Pascale Cossart,Paola Costelli,Safia Costes,Ana Coto-Montes,Eduardo Couve,Fraser P. Coxon,James M. Cregg,José L. Crespo,Marianne J. Cronjé,Ana Maria Cuervo,Joseph J. Cullen,Mark J. Czaja,Marcello D'Amelio,Arlette Darfeuille-Michaud,Lester M. Davids,Faith E. Davies,Massimo De Felici,John de Groot,Cornelis A. M. de Haan,Luisa De Martino,Angelo De Milito,Vincenzo De Tata,Jayanta Debnath,Alexei Degterev,Benjamin Dehay,Lea M.D. Delbridge,Francesca Demarchi,Yi Zhen Deng,Jörn Dengjel,Paul Dent,Donna Denton,Vojo Deretic,Shyamal D. Desai,Rodney J. Devenish,Mario Di Gioacchino,Gilbert Di Paolo,Chiara Di Pietro,Guillermo Díaz-Araya,Inés Díaz-Laviada,Maria T. Diaz-Meco,Javier Díaz-Nido,Ivan Dikic,Savithramma P. Dinesh-Kumar,Wen-Xing Ding,Clark W. Distelhorst,Abhinav Diwan,Mojgan Djavaheri-Mergny,Svetlana Dokudovskaya,Zheng Dong,Frank C. Dorsey,Victor E. Dosenko,James J. Dowling,Stephen J. Doxsey,Marlène Dreux,Mark E. Drew,Qiuhong Duan,Michel A. Duchosal,Karen Duff,Isabelle Dugail,Madeleine Durbeej,Michael Duszenko,Charles L. Edelstein,Aimee L. Edinger,Gustavo Egea,Ludwig Eichinger,N. Tony Eissa,Suhendan Ekmekcioglu,Wafik S. El-Deiry,Zvulun Elazar,Mohamed Elgendy,Lisa M. Ellerby,Kai Er Eng,Anna-Mart Engelbrecht,Simone Engelender,Jekaterina Erenpreisa,Ricardo Escalante,Audrey Esclatine,Eeva-Liisa Eskelinen,Lucile Espert,Virginia Espina,Huizhou Fan,Jia Fan,Qi-Wen Fan,Zhen Fan,Shengyun Fang,Yongqi Fang,Manolis Fanto,Alessandro Fanzani,Thomas Farkas,Jean-Claude Farré,Mathias Faure,Marcus Fechheimer,Carl G. Feng,Jian Feng,Qili Feng,Youji Feng,László Fésüs,Ralph Feuer,Maria E. Figueiredo-Pereira,Gian Maria Fimia,Diane C. Fingar,Steven Finkbeiner,Toren Finkel,Kim D. Finley,Filomena Fiorito,Edward A. Fisher,Paul B. Fisher,Marc Flajolet,Maria L. Florez-McClure,Salvatore Florio,Edward A. Fon,Francesco Fornai,Franco Fortunato,Rati Fotedar,Daniel H. Fowler,Howard S. Fox,Rodrigo Franco,Lisa B. Frankel,Marc Fransen,José M. Fuentes,Juan Fueyo,Jun Fujii,Kozo Fujisaki,Eriko Fujita,Mitsunori Fukuda,Ruth Furukawa,Matthias Gaestel,Philippe Gailly,Małgorzata Gajewska,Brigitte Galliot,Vincent Galy,Subramaniam Ganesh,Barry Ganetzky,Ian G. Ganley,Fen-Biao Gao,George F. Gao,Jinming Gao,Lorena García,Guillermo Garcia-Manero,Mikel Garcia-Marcos,Marjan Garmyn,Andrei L. Gartel,Evelina Gatti,Mathias Gautel,Thomas R. Gawriluk,Matthew E. Gegg,Jiefei Geng,Marc Germain,Jason E. Gestwicki,David A. Gewirtz,Saeid Ghavami,Pradipta Ghosh,Anna Maria Giammarioli,Alexandra Giatromanolaki,Spencer B. Gibson,Robert Gilkerson,Michael L. Ginger,Henry N. Ginsberg,Jakub Golab,Michael S. Goligorsky,Pierre Golstein,Candelaria Gomez-Manzano,Ebru Goncu,Céline Gongora,Claudio Gonzalez,Ramon Gonzalez,Cristina González-Estévez,Rosa A. González-Polo,Elena Gonzalez-Rey,Nikolai V. Gorbunov,Sharon M. Gorski,Sandro Goruppi,Roberta A. Gottlieb,Devrim Gozuacik,Giovanna Elvira Granato,Gary Grant,Kim N. Green,Aleš Gregorc,Frédéric Gros,Charles Grose,Thomas W. Grunt,Philippe Gual,Jun-Lin Guan,Kun-Liang Guan,Sylvie Guichard,Anna S. Gukovskaya,Ilya Gukovsky,Jan Gunst,Åsa B. Gustafsson,Andrew J. Halayko,Amber N. Hale,Sandra K. Halonen,Maho Hamasaki,Feng Han,Ting Han,Michael K. Hancock,Malene Hansen,Hisashi Harada,Masaru Harada,Stefan E. Hardt,J. Wade Harper,Adrian L. Harris,James Harris,Steven D. Harris,Makoto Hashimoto,Jeffrey A. Haspel,Jeffrey A. Haspel,Shin Ichiro Hayashi,Lori A. Hazelhurst,Congcong He,You-Wen He,Marie-Josée Hébert,Kim A. Heidenreich,Miep H. Helfrich,Gudmundur Vignir Helgason,Elizabeth P. Henske,Brian Herman,Paul K. Herman,Claudio Hetz,Sabine Hilfiker,Joseph A. Hill,Lynne J. Hocking,Paul Hofman,Thomas G. Hofmann,Jörg Höhfeld,Tessa L. Holyoake,Ming Huang Hong,David A. Hood,Gökhan S. Hotamisligil,Ewout J. Houwerzijl,Maria Høyer-Hansen,Bingren Hu,Chien-An Andy Hu,Hong-Ming Hu,Ya Hua,Canhua Huang,Ju Huang,Shengbing Huang,Wei-Pang Huang,Tobias B. Huber,Won-Ki Huh,Tai-Ho Hung,Ted R. Hupp,Gang Min Hur,James B. Hurley,Sabah N. A. Hussain,Patrick J. Hussey,Jung Jin Hwang,Seungmin Hwang,Atsuhiro Ichihara,Shirin Ilkhanizadeh,Ken Inoki,Takeshi Into,Valentina Iovane,Juan L. Iovanna,Nancy Y. Ip,Yoshitaka Isaka,Hiroyuki Ishida,Ciro Isidoro,Ken-ichi Isobe,Akiko Iwasaki,Marta Izquierdo,Yotaro Izumi,Panu Jaakkola,Marja Jäättelä,George R. Jackson,William T. Jackson,Bassam Janji,Marina Jendrach,Ju Hong Jeon,Eui-Bae Jeung,Hong Jiang,Hongchi Jiang,Jean X. Jiang,Ming Jiang,Qing Jiang,Xuejun Jiang,Alberto Jiménez,Meiyan Jin,Shengkan Jin,Cheol O. Joe,Terje Johansen,Daniel Johnson,Gail V.W. Johnson,Nicola L. Jones,Bertrand Joseph,Suresh K. Joseph,Annie M. Joubert,Gábor Juhász,Lucienne Juillerat-Jeanneret,Chang Hwa Jung,Yong-Keun Jung,Kai Kaarniranta,Allen Kaasik,Tomohiro Kabuta,Motoni Kadowaki,Katarina Kågedal,Yoshiaki Kamada,Vitaliy O. Kaminskyy,Harm H. Kampinga,Hiromitsu Kanamori,Chanhee Kang,Khong Bee Kang,Kwang Il Kang,Rui Kang,Yoon-A Kang,Tomotake Kanki,Thirumala-Devi Kanneganti,Haruo Kanno,Anumantha G. Kanthasamy,Arthi Kanthasamy,Vassiliki Karantza,Gur P. Kaushal,Susmita Kaushik,Yoshinori Kawazoe,Po-Yuan Ke,Po-Yuan Ke,John H. Kehrl,Ameeta Kelekar,Claus Kerkhoff,David Kessel,Hany Khalil,Jan A.K.W. Kiel,Amy A. Kiger,Akio Kihara,Deok Ryong Kim,Do Hyung Kim,Dong Hou Kim,Eun Kyoung Kim,Hyung Ryong Kim,Jae-Sung Kim,Jeong Hun Kim,Jin Cheon Kim,John Kim,Peter K. Kim,Seong Who Kim,Yong-Sun Kim,Yonghyun Kim,Adi Kimchi,Alec C. Kimmelman,Jason S. King,Timothy J. Kinsella,Vladimir Kirkin,Lorrie A. Kirshenbaum,Katsuhiko Kitamoto,Kaio Kitazato,Ludger Klein,Walter T. Klimecki,Jochen Klucken,Erwin Knecht,Ben C.B. Ko,Jan C. Koch,Hiroshi Koga,Jae-Young Koh,Young Ho Koh,Masato Koike,Masaaki Komatsu,Eiki Kominami,Hee Jeong Kong,Weijia Kong,Viktor I. Korolchuk,Yaichiro Kotake,Michael I. Koukourakis,Juan Kourí Flores,Attila L. Kovács,Claudine Kraft,Dimitri Krainc,Helmut Krämer,Carole Kretz-Remy,Carole Kretz-Remy,Anna M. Krichevsky,Guido Kroemer,Rejko Krüger,Oleg Krut,Nicholas T. Ktistakis,Chia Yi Kuan,Roza Kucharczyk,Ashok Kumar,Raj Kumar,Sharad Kumar,Mondira Kundu,Hsing Jien Kung,Tino Kurz,Ho Jeong Kwon,Albert R. La Spada,Albert R. La Spada,Frank Lafont,Trond Lamark,Jacques Landry,Jon D. Lane,Pierre Lapaquette,Jocelyn Laporte,Lajos László,Sergio Lavandero,Sergio Lavandero,Josée N. Lavoie,Robert Layfield,Pedro A. Lazo,Weidong Le,Laurent Le Cam,Daniel J. Ledbetter,Alvin J.X. Lee,Byung Wan Lee,Gyun Min Lee,Jongdae Lee,Ju-Hyun Lee,Michael Lee,Myung-Shik Lee,Sug Hyung Lee,Christiaan Leeuwenburgh,Patrick Legembre,Renaud Legouis,Michael Lehmann,Huan Yao Lei,Qun-Ying Lei,David A. Leib,José Leiro,John J. Lemasters,Antoinette Lemoine,Maciej S. Lesniak,Dina Lev,Victor V. Levenson,Beth Levine,Efrat Levy,Faqiang Li,Jun Lin Li,Lian Li,Sheng Li,Weijie Li,Xue-Jun Li,Yan Bo Li,Yi Ping Li,Chengyu Liang,Qiangrong Liang,Yung Feng Liao,Pawel P. Liberski,Andrew P. Lieberman,Hyunjung Jade Lim,Kah-Leong Lim,Kyu Lim,Chiou Feng Lin,Fu-Cheng Lin,Jian Lin,Jiandie D. Lin,Kui Lin,Wan-Wan Lin,Weei-Chin Lin,Yi-Ling Lin,Rafael Linden,Paul Lingor,Jennifer Lippincott-Schwartz,Michael P. Lisanti,Michael P. Lisanti,Paloma B. Liton,Bo Liu,Chun-Feng Liu,Kaiyu Liu,Leyuan Liu,Qiong A. Liu,Wei Liu,Young Chau Liu,Yule Liu,Richard A. Lockshin,Chun-Nam Lok,Sagar Lonial,Benjamin Loos,Gabriel Lopez-Berestein,Carlos López-Otín,Laura Lossi,Michael T. Lotze,Péter Löw,Binfeng Lu,Bingwei Lu,Bo Lu,Zhen Lu,Frederic Luciano,Nicholas W. Lukacs,Anders H. Lund,Melinda A. Lynch-Day,Yong Ma,Fernando Macian,Jeffrey P. MacKeigan,Kay F. Macleod,Frank Madeo,Luigi Maiuri,Maria Chiara Maiuri,Davide Malagoli,May Christine V. Malicdan,Walter Malorni,Na Man,Eva Maria Mandelkow,Stéphen Manon,Irena Manov,Kai Mao,Xiang Mao,Zixu Mao,Philippe Marambaud,Daniela Marazziti,Yves L. Marcel,Katie Marchbank,Piero Marchetti,Stefan J. Marciniak,Mateus Marcondes,Mohsen Mardi,Gabriella Marfe,Guillermo Mariño,Maria Markaki,Maria Markaki,Mark R. Marten,Seamus J. Martin,Camille Martinand-Mari,Wim Martinet,Marta Martinez-Vicente,Matilde Masini,Paola Matarrese,Saburo Matsuo,Raffaele Matteoni,Andreas Mayer,Nathalie M. Mazure,David J. McConkey,Melanie J. McConnell,Catherine McDermott,Christine McDonald,Gerald M. McInerney,Sharon L. McKenna,BethAnn McLaughlin,Pamela J. McLean,Christopher R. McMaster,G. Angus McQuibban,Alfred J. Meijer,Miriam H. Meisler,Alicia Meléndez,Thomas J. Melia,Gerry Melino,Gerry Melino,Maria Angeles Mena,Javier A. Menendez,Rubem F. S. Menna-Barreto,Manoj B. Menon,Fiona M. Menzies,Carol A. Mercer,Adalberto Merighi,Diane E. Merry,Stefania Meschini,Christian Meyer,Thomas F. Meyer,Chao-Yu Miao,Jun-Ying Miao,Paul A.M. Michels,Carine Michiels,Dalibor Mijaljica,Ana Milojkovic,Saverio Minucci,Clelia Miracco,Cindy K. Miranti,Ioannis Mitroulis,Keisuke Miyazawa,Noboru Mizushima,Baharia Mograbi,Simin Mohseni,Xavier Molero,Bertrand Mollereau,Faustino Mollinedo,Takashi Momoi,Iryna Monastyrska,Martha M. Monick,Mervyn J. Monteiro,Michael Moore,Rodrigo Mora,Kevin Moreau,Paula I. Moreira,Yuji Moriyasu,Jorge Moscat,Serge Mostowy,Jeremy C. Mottram,Tomasz Motyl,Charbel Moussa,Sylke Müller,Sylviane Muller,Karl Münger,Christian Münz,Leon Murphy,Maureen E. Murphy,Antonio Musarò,Indira U. Mysorekar,Eiichiro Nagata,Kazuhiro Nagata,Aimable Nahimana,Usha Nair,Toshiyuki Nakagawa,Kiichi Nakahira,Hiroyasu Nakano,Hitoshi Nakatogawa,Meera Nanjundan,Naweed I. Naqvi,Derek P. Narendra,Masashi Narita,Miguel Navarro,Steffan T. Nawrocki,Taras Y. Nazarko,Andriy Nemchenko,Mihai G. Netea,Thomas P. Neufeld,Paul A. Ney,Ioannis P. Nezis,Huu Phuc Nguyen,Daotai Nie,Ichizo Nishino,Corey Nislow,Ralph A. Nixon,Takeshi Noda,Angelika A. Noegel,Anna Nogalska,Satoru Noguchi,Lucia Notterpek,Ivana Novak,Tomoyoshi Nozaki,Tomoyoshi Nozaki,Nobuyuki Nukina,Thorsten Nürnberger,Beat Nyfeler,Keisuke Obara,Terry D. Oberley,Salvatore Oddo,Michinaga Ogawa,Toya Ohashi,Koji Okamoto,Nancy L. Oleinick,F. Javier Oliver,Laura J. Olsen,Stefan Olsson,Onya Opota,Timothy F. Osborne,Gary K. Ostrander,Kinya Otsu,Jing Hsiung James Ou,Mireille Ouimet,Michael Overholtzer,Bulent Ozpolat,Paolo Paganetti,Ugo Pagnini,Nicolas Pallet,Glen E. Palmer,Camilla Palumbo,Tianhong Pan,Theocharis Panaretakis,Udai Bhan Pandey,Zuzana Papackova,Issidora S. Papassideri,Irmgard Paris,Irmgard Paris,Junsoo Park,Ohkmae K. Park,Jan B. Parys,Katherine R. Parzych,Susann Patschan,W. Cam Patterson,Sophie Pattingre,John M. Pawelek,Jianxin Peng,David H. Perlmutter,Ida Perrotta,George Perry,Shazib Pervaiz,Matthias Peter,Godefridus J. Peters,Morten Petersen,Goran Petrovski,James M. Phang,Mauro Piacentini,Philippe Pierre,Valérie Pierrefite-Carle,Gérard Pierron,Ronit Pinkas-Kramarski,Antonio Piras,Natik Piri,Leonidas C. Platanias,Stefanie Pöggeler,Marc Poirot,Angelo Poletti,Christian Poüs,Mercedes Pozuelo-Rubio,Mette Prætorius-Ibba,Anil Prasad,Mark Prescott,Muriel Priault,Nathalie Produit-Zengaffinen,Ann Progulske-Fox,Tassula Proikas-Cezanne,Serge Przedborski,Karin Przyklenk,Rosa Puertollano,Julien Puyal,Shu-Bing Qian,Liang Qin,Zheng-Hong Qin,Susan E. Quaggin,Nina Raben,Hannah Rabinowich,Simon W. Rabkin,Irfan Rahman,Abdelhaq Rami,Georg Ramm,Glenn Randall,Felix Randow,V. Ashutosh Rao,Jeffrey C. Rathmell,Brinda Ravikumar,Swapan K. Ray,Bruce H. Reed,John C. Reed,Fulvio Reggiori,Anne Régnier-Vigouroux,Anne Régnier-Vigouroux,Andreas S. Reichert,John J. Reiners,Russel J. Reiter,Jun Ren,José L. Revuelta,Christopher J. Rhodes,Konstantinos Ritis,Elizete Rizzo,Jeffrey Robbins,Michel Roberge,Hernan Roca,Maria Carmela Roccheri,Stéphane Rocchi,H. Peter Rodemann,Santiago Rodríguez de Córdoba,Bärbel Rohrer,Igor B. Roninson,Kirill V. Rosen,Magdalena Rost-Roszkowska,Mustapha Rouis,Kasper M.A. Rouschop,Francesca Rovetta,Brian P. Rubin,David C. Rubinsztein,Klaus Ruckdeschel,Edmund B. Rucker,Assaf Rudich,Emil Rudolf,Nelson Ruiz-Opazo,Rossella Russo,Tor Erik Rusten,Kevin M. Ryan,Stefan W. Ryter,David M. Sabatini,Junichi Sadoshima,Tapas Saha,Tatsuya Saitoh,Hiroshi Sakagami,Yasuyoshi Sakai,Ghasem Hosseini Salekdeh,Paolo Salomoni,Paul M. Salvaterra,Guy S. Salvesen,Rosa Salvioli,Anthony Sanchez,José Antonio Sánchez-Alcázar,Ricardo Sánchez-Prieto,Marco Sandri,Uma Sankar,Poonam Sansanwal,Laura Santambrogio,Shweta Saran,Sovan Sarkar,Minnie M. Sarwal,Chihiro Sasakawa,Ausra Sasnauskiene,Miklós Sass,Ken Sato,Miyuki Sato,Anthony H.V. Schapira,Michael Scharl,Hermann M. Schätzl,Wiep Scheper,Stefano Schiaffino,Claudio Schneider,Marion Schneider,Regine Schneider-Stock,Patricia V. Schoenlein,Daniel F. Schorderet,Christoph Schüller,Gary K. Schwartz,Luca Scorrano,Linda Sealy,Per Ottar Seglen,Juan Segura-Aguilar,Iban Seiliez,Oleksandr Seleverstov,Christian Sell,Jong Bok Seo,Duska Separovic,Vijayasaradhi Setaluri,Takao Setoguchi,Carmine Settembre,John J. Shacka,Mala Shanmugam,Irving M. Shapiro,Eitan Shaulian,Reuben J. Shaw,James H. Shelhamer,Han-Ming Shen,Wei-Chiang Shen,Zu-Hang Sheng,Yang Shi,Kenichi Shibuya,Yoshihiro Shidoji,Jeng-Jer Shieh,Chwen Ming Shih,Yohta Shimada,Shigeomi Shimizu,Takahiro Shintani,Orian S. Shirihai,Gordon C. Shore,Andriy A. Sibirny,Andriy A. Sibirny,Stan B. Sidhu,Beata Sikorska,Elaine C.M. Silva-Zacarin,Alison Simmons,Anna Katharina Simon,Hans-Uwe Simon,Cristiano Simone,Anne Simonsen,David A. Sinclair,Rajat Singh,Debasish Sinha,Frank A. Sinicrope,Agnieszka Sirko,Parco M. Siu,Efthimios Sivridis,Vojtech Skop,Vladimir P. Skulachev,Ruth S. Slack,Soraya S. Smaili,Duncan R. Smith,Maria S. Soengas,Thierry Soldati,Xueqin Song,Anil K. Sood,Tuck Wah Soong,Federica Sotgia,Stephen A. Spector,Stephen A. Spector,Claudia Spies,Wolfdieter Springer,Srinivasa M. Srinivasula,Leonidas Stefanis,Joan S. Steffan,Ruediger Stendel,Harald Stenmark,Anastasis Stephanou,Stephan T. Stern,Cinthya Sternberg,Björn Stork,Peter Strålfors,Carlos S. Subauste,Xinbing Sui,David Sulzer,Jiaren Sun,Shi-Yong Sun,Zhi Jun Sun,Joseph J.Y. Sung,Kuninori Suzuki,Toshihiko Suzuki,Michele S. Swanson,Charles Swanton,Sean T. Sweeney,Lai King Sy,Gyorgy Szabadkai,Ira Tabas,Heinrich Taegtmeyer,Marco Tafani,Krisztina Takács-Vellai,Yoshitaka Takano,Kaoru Takegawa,Genzou Takemura,Fumihiko Takeshita,Nicholas J. Talbot,Kevin S. W. Tan,Keiji Tanaka,Kozo Tanaka,Daolin Tang,Dingzhong Tang,Isei Tanida,Bakhos A. Tannous,Nektarios Tavernarakis,Graham S. Taylor,Gregory A. Taylor,J. Paul Taylor,Ance S. Terada,Alexei Terman,Gianluca Tettamanti,Karin Thevissen,Craig B. Thompson,Andrew Thorburn,Michael Thumm,Feng Feng Tian,Yuan Tian,Glauco P. Tocchini-Valentini,Aviva M. Tolkovsky,Yasuhiko Tomino,Lars Tönges,Sharon A. Tooze,Cathy Tournier,John Tower,Roberto Towns,Vladimir Trajkovic,Leonardo H. Travassos,Ting Fen Tsai,Mario P. Tschan,Takeshi Tsubata,Allan Tsung,Boris Turk,Lorianne S. Turner,Suresh C. Tyagi,Yasuo Uchiyama,Takashi Ueno,Midori Umekawa,Rika Umemiya-Shirafuji,Vivek K. Unni,Maria I. Vaccaro,Enza Maria Valente,Enza Maria Valente,Greet Van den Berghe,Ida J. van der Klei,Wouter G. van Doorn,Linda F. van Dyk,Marjolein van Egmond,Leo A. van Grunsven,Peter Vandenabeele,Wim Vandenberghe,Ilse Vanhorebeek,Eva C. Vaquero,Guillermo Velasco,Tibor Vellai,Jose Miguel Vicencio,Richard D. Vierstra,Miquel Vila,Cécile Vindis,Cécile Vindis,Giampietro Viola,Maria Teresa Viscomi,Olga V. Voitsekhovskaja,Clarissa von Haefen,Marcela Votruba,Keiji Wada,Richard Wade-Martins,Cheryl L. Walker,Craig M. Walsh,Jochen Walter,Xiang Bo Wan,Aimin Wang,Chenguang Wang,Dawei Wang,Fan Wang,Fen Wang,Guanghui Wang,Haichao Wang,Hong Gang Wang,Horng-Dar Wang,Jin Wang,Ke Wang,Mei Wang,Richard C. Wang,Xinglong Wang,Xuejun Wang,Ying Jan Wang,Yipeng Wang,Zhen Wang,Zhigang Charles Wang,Zhi-Nong Wang,Derick G. Wansink,Diane M. Ward,Hirotaka Watada,Sarah Waters,Paul Webster,Lixin Wei,Conrad C. Weihl,William A. Weiss,Scott M. Welford,Longping Wen,Caroline A. Whitehouse,J. Lindsay Whitton,Alexander J. Whitworth,Thomas Wileman,John W. Wiley,Simon Wilkinson,Dieter Willbold,Roger L. Williams,Peter R. Williamson,Bradly G. Wouters,Chenghan Wu,Dao Cheng Wu,William K.K. Wu,Andreas Wyttenbach,Ramnik J. Xavier,Zhijun Xi,Pu Xia,Gengfu Xiao,Zhiping Xie,Zhonglin Xie,Da Zhi Xu,Jianzhen Xu,Liang Xu,Xiaolei Xu,Ai Yamamoto,Akitsugu Yamamoto,Shunhei Yamashina,Michiaki Yamashita,Xianghua Yan,Mitsuhiro Yanagida,Dun-Sheng Yang,Elizabeth Yang,Jin Ming Yang,Shi Yu Yang,Wannian Yang,Wei Yuan Yang,Zhifen Yang,Meng-Chao Yao,Tso-Pang Yao,Behzad Yeganeh,Wei Lien Yen,Jia Jing Yin,Xiao Ming Yin,Ook Joon Yoo,Gyesoon Yoon,Seung Yong Yoon,Tomohiro Yorimitsu,Yuko Yoshikawa,Tamotsu Yoshimori,Kohki Yoshimoto,Ho Jin You,Richard J. Youle,Anas Younes,Li Yu,Long Yu,Seong-Woon Yu,Wai Haung Yu,Zhi-Min Yuan,Zhenyu Yue,Cheol-Heui Yun,Michisuke Yuzaki,Olga Zabirnyk,Elaine Silva-Zacarin,E. David Zacks,Ldad Zacksenhaus,Nadia Zaffaroni,Zahra Zakeri,Herbert J. Zeh,Scott Zeitlin,Hong Zhang,Hui Ling Zhang,Jianhua Zhang,Jing Pu Zhang,Lin Zhang,Long Zhang,Ming Yong Zhang,Xudong Zhang,Mantong Zhao,Yi Fang Zhao,Ying Zhao,Zhizhuang J. Zhao,Xiaoxiang Zheng,Boris Zhivotovsky,Qing Zhong,Cong Zhao Zhou,Changlian Zhu,Wei-Guo Zhu,Xiao Feng Zhu,Xiongwei Zhu,Yuangang Zhu,Teresa Zoladek,Wei-Xing Zong,Antonio Zorzano,Jürgen Zschocke,Brian S. Zuckerbraun +1287 more
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur,Kevin J. Pearson,Nathaniel O Price,Hamish A. Jamieson,Carles Lerin,Avash Kalra,Vinayakumar Prabhu,Joanne S. Allard,Guillermo López-Lluch,Kaitlyn N. Lewis,Paul J. Pistell,Suresh Poosala,Kevin G. Becker,Olivier Boss,Dana M. Gwinn,Mingyi Wang,Sharan Ramaswamy,Kenneth W. Fishbein,Richard G. Spencer,Edward G. Lakatta,David G. Le Couteur,Reuben J. Shaw,Plácido Navas,Pere Puigserver,Donald K. Ingram,Rafael de Cabo,David A. Sinclair +26 more
TL;DR: It is shown that resveratrol shifts the physiology of middle-aged mice on a high-calorie diet towards that of mice onA standard diet and significantly increases their survival and point to new approaches for treating obesity-related disorders and diseases of ageing.
Journal ArticleDOI
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
Konrad T. Howitz,Kevin J. Bitterman,Haim Y. Cohen,Dudley W. Lamming,Siva Lavu,Jason G. Wood,Robert E. Zipkin,Phuong Chung,Anne Kisielewski,Li-Li Zhang,Brandy Scherer,David A. Sinclair +11 more
TL;DR: The potent activator resveratrol, a polyphenol found in red wine, lowers the Michaelis constant of SIRT1 for both the acetylated substrate and NAD+, and increases cell survival by stimulating Sirt1-dependent deacetylation of p53.
Journal ArticleDOI
Therapeutic potential of resveratrol: the in vivo evidence.
Joseph A. Baur,David A. Sinclair +1 more
TL;DR: A comprehensive and critical review of the in vivo data on resveratrol is provided, and its potential as a therapeutic for humans is considered.
Journal ArticleDOI
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
Anne Brunet,Lora B. Sweeney,J. Fitzhugh Sturgill,Katrin F. Chua,Paul L. Greer,Yingxi Lin,Hien Tran,Sarah E. Ross,Raul Mostoslavsky,Haim Y. Cohen,Linda Hu,Hwei-Ling Cheng,Mark P. Jedrychowski,Steven P. Gygi,David A. Sinclair,Frederick W. Alt,Michael E. Greenberg +16 more
TL;DR: One way in which members of the Sir2 family of proteins may increase organismal longevity is by tipping FOXO-dependent responses away from apoptosis and toward stress resistance.