Scott Brown

TL;DR: Endovascular thrombectomy is of benefit to most patients with acute ischaemic stroke caused by occlusion of the proximal anterior circulation, irrespective of patient characteristics or geographical location, and will have global implications on structuring systems of care to provide timely treatment.

TL;DR: The period in which endovascular thrombectomy is associated with benefit, and the extent to which treatment delay is related to functional outcomes, mortality, and symptomatic intracranial hemorrhage are characterized are characterized.

TL;DR: Estimated ischaemic core volume was independently associated with functional independence and functional improvement but did not modify the treatment benefit of endovascular thrombectomy over standard medical therapy for improved functional outcome.

TL;DR: The benefit of endovascular therapy in HERMES was strongly associated with increasing degrees of reperfusion defined by eTICI, which identified meaningful distinctions in clinical outcomes and may be used in future studies and routine practice.

TL;DR: Better outcomes after endovascular thrombectomy were associated with GA, after adjustment for baseline prognostic variables, indicating that treatment should not be withheld in those who require anaesthesia for medical reasons.